d-galactosamine

β-D-Galactosamine pentaacetate serves as an intermediate in the synthesis of tri-antennary N-acetylgalactosamine ligands. Additionally, β-D-Galactosamine pentaacetate is utilized in research focused on liver-targeted delivery of siRNA.

D(+)-Galactosamine hydrochloride is a well-established experimental toxin that induces liver injury primarily by generating free radicals and depleting UTP nucleotides, and it can be used to establish lipopolysaccharide/D-Galactosamine-induced hepatitis or acute liver injury models.

N-Acetyl-D-galactosamine-6-phosphate (disodium) is a galactosamine phosphate involved in galactose metabolism and the phosphotransferase system (PTS), which can be hydrolyzed by NagA.

N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans.

N-Acetyl-D-Galactosamine-[13C6] (Standard) is a reference standard of N-Acetyl-D-Galactosamine-[13C6] intended for quantitative analysis, quality control, and related biochemical research applications.

1β-Methylseleno-N-acetyl-D-galactosamine (MeSebGalNac) is a nucleoside metabolite.

D-Galactosamine pentaacetate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

O-Methyl-N-acetyl-2-deoxy-α-D-galactosamine (O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine) is a biochemical reagent utilized in glycoscience research. This field explores the structure, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, glycan formation and degradation enzymology, and protein-glycan recognition, with significant connections to basic research, biomedicine, and biotechnology.

β-D-Galactosyl-(1→3)-N-acetyl-D-galactosamine is a biochemical reagent used in glycoscience research. Glycoscience studies the structures, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan interactions, and the roles of glycans in biological systems. This field is closely connected to basic research, biomedicine, and biotechnology.

N-Acetyl-D-galactosamine-4-O-sulfate sodium salt is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins).

GalNac-L96 triethylamine salt is a trivalent N-acetylgalactosamine (GalNAc) ligand for the asialoglycoprotein receptor (ASGPR).

GalNAc-L96 is a triantennary N-acetylgalactosamine (GalNAc) ligand for asialoglycoprotein receptors (ASGPR) that lacks sialic acid.

UDP-GalNAc disodium is a key sugar nucleotide and serves as the catalytic substrate of EpsC115 (a truncated mutant protein of extracellular polymeric substance (EPS) with amino acids 1–115 at the N-terminus). It is a universal glycosyl donor for various N-acetylgalactosaminyltransferases, mediating the transfer of GalNAc groups from nucleotide sugars to carbohydrate or polypeptide receptors and providing essential glycosyl precursors for various glycosylation modification reactions. At present, UDP-GalNAc disodium has been widely applied in mechanism research of colorectal cancer, breast cancer and other tumors.

DNJNAc, also known as 2-Acetamido-1,2-dideoxynojirimycin, is a highly potent and specific inhibitor of β-hexosaminidase (HEX). HEX enzymes catalyze the hydrolysis of terminal non-reducing N-acetyl-β-D-glucosamine (GlcNAc) and N-acetyl-β-D-galactosamine (GalNAc) residues from glycoconjugates such as glycoproteins, gangliosides, and glycosaminoglycans. HEX secreted by chondrocytes into the extracellular space contributes to cartilage matrix degradation, and HEX activity is elevated in the synovial fluid of osteoarthritis patients.

Tubuloside A ( 8.6 microM) can inhibit D-galactosamine-induced death of hepatocytes. Tubuloside A has NO radical-scavenging activity, which possibly contributes to its anti-inflammatory effects.Tubuloside A shows stronger free radical scavenging activitie

Inonotusol F, a triterpene extracted from Inonotus obliquus, exhibits hepatoprotective properties by mitigating D-galactosamine-induced damage in WB-F344 cells [1].

Glomeratide A, a benzophenone C-glucoside, exhibits hepatoprotective properties and safeguards rat liver epithelial stem-like cells from d-galactosamine-induced hepatotoxicity.

Fulvotomentoside B is a natural saponin discovered in Lactobacillus flavus, suitable for biochemical experiments and medicinal synthesis research.

Cholesteryl Hemisuccinate Tris Salt is an acidic cholesteryl ester with hepatoprotective and anticancer activity.Cholesteryl hemisuccinate is a membrane stabilizer in dipalmitoylphosphatidylcholine liposomes containing Chaikosaponin-d, which enhances the anticancer efficacy of cisplatin.Cholesteryl hemisuccinate possesses antitumor activity, inhibits tumor Cholesteryl hemisuccinate has antitumor activity, inhibits tumor growth, inhibits the hepatotoxicity of acetaminophen (AAP) and prevents AAP-induced apoptosis of hepatocytes.Cholesteryl hemisuccinate protects rodents against the toxic effects of acetaminophen, adriamycin, carbon tetrachloride, chloroform, and galactosamine.

Tubuloside A (Standard) is a reference standard for research and analysis in studies involving Tubuloside A. Tubuloside A ( 8.6 microM) can inhibit D-galactosamine-induced death of hepatocytes. Tubuloside A has NO radical-scavenging activity, which possibly contributes to its anti-inflammatory effects.Tubuloside A shows stronger free radical scavenging activities than alpha-tocopherol on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide anion radical (O2-.).

Leonoside F is a phenylethanoid compound isolated from the aerial parts of Leonurus japonicus (Houtt.), offering protective effects for hepatocytes against chemically induced damage. At a concentration of 1×10⁻⁵ M, it exhibits significant hepatoprotective activity against D-galactosamine-induced damage in HL-7702 liver cells, achieving an inhibition rate of 30.9%.

5-Deoxystrigol is a highly active Striga germination stimulant. It has a protective effect on D-galactosamine (D-GalN) induced mice acute liver injury and has a protective effect on CCl4 induced mice acute liver injury.

1,3,4,6-Tetra-O-acetyl-β-D-galactosamine (hydrochloride) is a biochemical reagent utilized in glycobiology research. This field examines the structure, synthesis, biology, and evolution of sugars, involving carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan interactions, and the roles of glycans in biological systems. It is closely associated with basic research, biomedicine, and biotechnology.