cyclo-c

Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycle. Cytarabine agent also inhibits DNA polymerase, resulting in a decrease in DNA replication and repair. Compared to cytarabine, a more prolonged, consistent cytarabine-mediated therapeutic effect may be achieved with ancitabine because of the slow hydrolytic conversion of ancitabine to cytarabine.

cyclo-Cannabigerol (cyclo-CBG) is the primary metabolite of Cannabigerol formed via cytochrome P450 metabolism. cyclo-Cannabigerol exhibits mild anti-inflammatory activity.

Cyclo-cadagac is a cyclic heptapeptide.

TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor targeting HIF-1 heterodimerization to mitigate hypoxia signaling within cancer cells. It effectively disrupts the protein-protein interaction between HIF-1α and HIF-1β, with an inhibitory concentration (IC 50) of 1.3 μM [1].

Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50 = 1.3 μM). Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cance

Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation, improving cognitive, autistic and epileptic phenotypes in mouse models of creatine transporter deficiency (CTD).

Cyclocarioside B is a useful organic compound for research related to life sciences. The catalog number is T123910 and the CAS number is 934226-74-1.

Cyclocalopin A is a useful organic compound for research related to life sciences and the catalog number is T124792.

Cyclocarioside J is a useful organic compound for research related to life sciences. The catalog number is T125649 and the CAS number is 1644624-86-1.

Cyclocarioside D is a useful organic compound for research related to life sciences. The catalog number is T125917 and the CAS number is 1403937-41-6.

Cyclocarposide is a useful organic compound for research related to life sciences and the catalog number is T131539.

Cyclocumarol is an anticoagulant with less potency than warfarin. Improper use of this compound may cause bleeding.

Ancitabine is an antitumour drug that improves Hailey-Hailey disease-related phenotypes in yeast models. It is metabolised to cytarabine in vivo and inhibits DNA synthesis, primarily used for treating acute leukaemia.

Cyclochlorotine is a mycotoxin produced by Penicillium insularum, which can cause liver injury and has carcinogenic properties.

Cyclocreatine phosphate (CCrP) is an anti-tumor agent and the proposed active form of cyclocreatine (CCr), a substrate analogue of creatine kinase. As potent cardioprotective drugs, cyclocreatine and its water-soluble derivative CCrP can be used for cancer research[1].

Davercin (Erythromycin Cyclocarbonate), a Erythromycin derivative, exhibits efficacy against both Gram-positive and select Gram-negative microorganisms.

β-Cyclocitral belongs to the class of organic compounds.

Cyclocephaloside II is a natural product extracted from the roots of Astragalus brachypterus and Astragalus microcephalus, belonging to the class of cycloalkane triterpenoid saponins with potential biological activities. Astragalus saponin has the effect of improving myocardial function.

Cyclocarioside I is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

Cyclocarioside H is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

Cyclocerberidol is a natural product for research related to life sciences. The catalog number is TN3739 and the CAS number is 126594-66-9.

Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong inhibition of arachidonic acid (AA)- and collagen-induced platelet aggregation.

Cyclocurcumin is a minor curcuminoid derived from the rhizome of Curcuma longa that differs structurally from curcumin despite sharing the same molecular formula (C21H20O6), Cyclocurcumin features an α,β-unsaturated dihydropyranone moiety that drives trans–cis photoisomerization instead of the diketone/keto–enol tautomerism characteristic of curcumin. Cyclocurcumin demonstrates potent biochemical activities, including selective inhibition of human aromatase (CYP19A1) with an IC50 of 4.43 μM—approximately fivefold stronger than curcumin—making it valuable for studying estrogen-related pathways, and uniquely stimulates melanogenesis and melanin export in both melanocyte and melanoma models, positioning it as a promising research tool for investigating hypopigmentary skin disorders.

O-Acetylcyclocalopin A is a natural product. The catalog number is TN4684 and the CAS number is 486430-93-7. O-Acetylcyclocalopin A can be used as a reference standard.