contrast

Iopamidol (SQ-13396) is a benzenedicarboxamide compound. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic.

Gadopentetic acid (gadolinium complex) (Gd-DTPA) is an paramagnetic contrast agent commonly implemented by a bolus intravenous injection (i.v.) in Dynamic contrast-enhanced MRI (DCE-MRI) studies.

iosimide is a novel nonionic monomer contrast agent that can induce MV in cells.

Iodipamide (Iodipamic acid) is a water-soluble radiographic contrast media for intravenous cholangiography and cholecystography.

Meglumine (Meglumin), a derivative of sorbitol, is used in conjunction with iodinated organic compounds as contrast medium.

Iopanoic acid is an iodine contrast agent and a 5'-Deiodinase inhibitor.

Iodixanol (Visipaque) is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography.

Sodium diatrizoate is an iodinated radiopaque X-ray contrast agent used as a diagnostic aid in angiography, urography, and radiography. It induces mitochondrial renewal and oxidative stress through calcium dysregulation and activates apoptosis.

Diatrizoic Acid (Amidotrizoic acid) is an organic, iodinated radiopaque X-ray contrast medium used in diagnostic radiography.

Iohexol is an X-ray contrast agent containing varying concentrations of iohexol, which can be used for a variety of imaging applications.

Gadoteridol (Gd-HP-DO3A) is a gadolinium-based MRI contrast agent that can be used for central nervous system imaging.

Ethylene thiourea (NCIC03372) is a pesticide used in fruit and vegetable production. Ethylene thiourea is also used as a novel contrast agent for MRI studies based on proton chemical exchange-dependent saturation transfer.

Diatrizoate meglumine (Renocal) is the meglumine salt of diatrizoate, it is an organic, iodinated, radiopaque X-ray contrast medium used in diagnostic radiography.

Ferumoxytol (Magnetic Black) is a non-gadolinium based contrast agent for use in magnetic resonance imaging applications.

Gadolinium(III) chloride hexahydrate is a contrast agent in magnetic resonance imaging and can be used in medicine, magnetic resonance imaging, liquid crystal displays and other fields. Gadolinium(III) chloride hexahydrate can be used to synthesize complexes and nanomaterials.

Acetrizoic acid (Urokon) is the first monomeric ionic compound used as an X-ray contrast agent.

Ifenprodil glucuronide, a derivative of Ifenprodil, is a vasodilator and an inhibitor of platelet aggregation. In contrast to Ifenprodil, Ifenprodil glucuronide does not affect platelet aggregation nor arterial contraction.

BHPI is a potent ERα inhibitor that blocks nuclear estrogen–ERα-regulated gene expression effectively. It triggers sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor, notably the unfolded protein response (UPR), and consistently inhibits protein synthesis. With an IC50 value targeting ERα, BHPI's mechanism involves the rapid hyperactivation of PLCγ on the plasma membrane in ERα(+) cancer cells, which produces inositol 1,4,5-triphosphate (IP3). This, in turn, opens EnR IP3R calcium channels, leading to a rapid depletion of EnR Ca(2+) stores. SIGNIFICANTLY, BHPI alters estrogen-ERα's usual effect of causing mild and transient UPR activation by inducing a severe and prolonged UPR activation, transforming the UPR from a protective to a toxic response.

Iopromide (Iopromidum) is a low osmolar, non-ionic contrast agent for intravascular use.

Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or liver metastasis on T1-weighted imaging. It is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary system. It accumulates in normal, fun

Gemcitabine elaidate (CP-4126) hydrochloride is a lipophilic pro-drug of Gemcitabine, converted to Gemcitabine by esterases for phosphorylation. Unlike gemcitabine, Gemcitabine elaidate hydrochloride can be administered orally, displaying schedule and dose-dependent toxicity and antitumor activity.

Metrizoic acid is an ionic contrast medium. Metrizoic acid displays high osmolality and has a risk of inducing allergic reactions.

PK14105 has been evaluated biologically as a potential radioligand for positron emission tomography (PET) studies targeting peripheral benzodiazepine binding sites (PBBS) receptors. When administered to rats with unilaterally lesioned striata, PK14105 was observed to quickly cross the blood-brain barrier, displaying significant radioactivity retention in the lesioned striatum, in contrast to the unlesioned striatum or cerebellar vermis. Additionally, PK14105 has the capability to inhibit receptor ligands, calcium channel ligands, and co-transporters in all salivary glands.

EC-17 (disodium salt), a folate receptor alpha (FRα) targeting contrast agent, exhibits fluorescent properties within the visible light spectrum, characterized by peak excitation and emission wavelengths of 470 520 nm, respectively.