contraception

Norethindrone (Norethisterone) is a synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception.

Ulipristal acetate (CDB-2914) is an orally bioavailable selective progesterone receptor modulator with anti-progesterone activity. It binds to the progesterone receptor (PR), inhibiting PR-mediated gene expression and interfering with progesterone activity in the reproductive system, potentially suppressing the growth of uterine leiomyomatosis. Additionally, ulipristal can be used as emergency contraception by inhibiting or delaying ovulation and affecting endometrial tissue.

Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives.

Norgestrel (WY-3707) is a synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes.

ALK inhibitor 1 is a selective ALK kinase inhibitor.

Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.

Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.

Gamendazole is a novel drug candidate for male contraception. It has been shown to reduce fertility in male rats without affecting testosterone levels.

Org-31710 is a progesterone receptor antagonist potentially for contraception.

Org-33628, a progesterone receptor antagonist, is used potentially for female contraception.

ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.

BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT. It is utilized in research related to contraception, cancer, and heart disease [1].

Norethindrone-2,2,4,6,6,10-d6 is a deuterated compound of Norethindrone. Norethindrone has a CAS number of 68-22-4. Norethindrone is a synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception.

Norethindrone (Ethynyl-13C2) is the 13C labeled compound of Norethindrone. Norethindrone has a CAS number of 68-22-4. Norethindrone is a synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception.