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(5)
By Target- Molecular Glues
- Apoptosis(2)
- E1/E2/E3 Enzyme(1)
- IKZF(1)
- Ligand for E3 Ligase(1)
- Wee1(1)
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By TargetFilter
Search Result
Results for "
celmod
" in TargetMol Product Catalog- Inhibitors & Agonists5
- PROTAC Products4
Iberdomide
Cited
CC-220
T77911323403-33-3
Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
- $39
Size
QTY
CitedMezigdomide
CC-92480
T107032259648-80-9In house
Mezigdomide (CC-92480) is a potent, novel, selective and active cereblon E3 ubiquitin ligase modulator (CELMoD) that acts as a molecular glue. Mezigdomide has anti-myeloma activity. [1]
- $118
Size
QTY
BMS986449, BMS 986449
T204091
BMS-986449 is an IKZF2 (Helios)/IKZF4 (Eos) degrader and CELMoD molecular glue. It redirects the interaction between the E3 ubiquitin ligase Cereblon and Helios/Eos in primary Treg cells, inducing their degradation, and may be utilised for anti-tumour immunotherapy.
- $209
Size
QTY
BMS986470, BMS 986470
T2104893036554-12-5
BMS-986470 is a CRBN E3 ubiquitin ligase modulator (CELMoD) that activates fetal hemoglobin (HbF). It is an orally available molecular glue degradator targeting ZBTB7A and WIZ protein degradation, thereby inducing gamma globin synthesis and activating HbF. It is applicable for studying sickle cell disease (SCD).
- $218
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QTY
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