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(2)
By Target- Apoptosis
- Molecular Glues(2)
- E1/E2/E3 Enzyme(1)
- IKZF(1)
- Ligand for E3 Ligase(1)
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Results for "
celmod
" in TargetMol Product Catalog- Inhibitors & Agonists3
- PROTAC Products3
Mezigdomide
CC-92480
T107032259648-80-9In house
Mezigdomide (CC-92480) is a potent, novel, selective and active cereblon E3 ubiquitin ligase modulator (CELMoD) that acts as a molecular glue. Mezigdomide has anti-myeloma activity. [1]
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Iberdomide
CC-220
T77911323403-33-3
Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
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BMS986449
T204091
BMS-986449 is a CELMoD-type molecular gel that remodels the function of regulatory T cells (Treg) and enhances their anti-tumor immune responses by directing the E3 ubiquitin ligase, Cereblon, to target the degradation of IKZF2 (Helios) and IKZF4 (Eos). BMS-986449 has potential application in the study of advanced solid tumors.
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