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  • Molecular Glues
    (5)
  • Apoptosis
    (2)
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Results for "

celmod

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    5
    TargetMol | Inhibitors_Agonists
  • PROTAC Products
    4
    TargetMol | PROTAC
Iberdomide
CC-220
T77911323403-33-3
Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
  • $39
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TargetMol | Citations Cited
Mezigdomide
CC-92480
T107032259648-80-9In house
Mezigdomide (CC-92480) is a potent, novel, selective and active cereblon E3 ubiquitin ligase modulator (CELMoD) that acts as a molecular glue. Mezigdomide has anti-myeloma activity. [1]
  • $118
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BMS-986449
BMS986449, BMS 986449
T204091
BMS-986449 is an IKZF2 (Helios)/IKZF4 (Eos) degrader and CELMoD molecular glue. It redirects the interaction between the E3 ubiquitin ligase Cereblon and Helios/Eos in primary Treg cells, inducing their degradation, and may be utilised for anti-tumour immunotherapy.
  • $209
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BMS-986470
T2104893036554-12-5
BMS-986470 is a CRBN E3 ubiquitin ligase modulator (CELMoD) that can activate fetal hemoglobin (HbF). It is an orally-administered dual-target molecular glue degrader, primarily acting on ZBTB7A and WIZ proteins. This compound can significantly promote the expression of γ-globin and has significant application value in the study of sickle cell disease (SCD).
  • $218
8-10 weeks
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