bxa

Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.

7,8,9-Trimethoxy-10H-1,3-dioxolo[4,5-b]xanthen-10-one is a useful organic compound for research related to life sciences and the catalog number is T125216.

LIBX-A401 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4) with an IC50 value of 0.38 μM. It selectively inhibits ACSL4 over ACSL3 (IC50 exceeding 50 μM) and PPARγ (IC50 exceeding 10 μM).

LIBX-A403 (Compound 21) is a highly selective inhibitor of acyl-CoA synthetase long-chain family member 4 (ACSL4) with an IC50 of 0.049 μM. It prevents ACSL4-mediated pro-ferroptotic phospholipid remodeling. LIBX-A403 shows potential for research in cancer, such as triple-negative breast cancer, and neurodegenerative disorders like Parkinson's disease.

LIBX-A402 (Compound 15b) is a selective ACSL4 inhibitor with an IC50 of 0.33 μM. It notably safeguards MDA-MB-231 and LUHMES cells from ferroptosis. LIBX-A402 is applicable in research focused on cancer, ischemia-reperfusion injury, and neurodegenerative disorders such as Parkinson's disease.

GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.