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(1)
By Target- Anti-infection
- Apoptosis(1)
- Autophagy(1)
- JAK(1)
- STAT(1)
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Results for "
brevilin a
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Natural Products1
Brevilin A 
T467216503-32-5
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAKs activity and blocking STAT3 signaling (IC50 = 10.6 μM) in Cancer Cells.Brevilin A induces apoptosis and autophagy via mitochondrial pathway and PI3K AKT mTOR inactivation in colon adenocarcinoma cell CT26.antitumour
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