bptf

DC-BPi-03 is a potent BPTF-BRD inhibitor, exhibiting an IC50 of 698.3 nM and a Kd of 2.81 μM.

BPTF-IN-BZ1 is a BPTF inhibitor that possesses a high potency with a Kd of 6.3 nM.

BPTF-IN-1 (compound AU1) is a selective BPTF bromodomain inhibitor (Kd: 2.8 μM) that is more selective for BPTF than for the BRD4 bromodomain.BPTF-IN-1 has an antimalarial effect.

NVS-BPTF-1 is a specific inhibitor of bromodomain and PHD finger containing transcription factor (BPTF), exhibiting a dissociation constant (K_D) of 71 nM [1].

TP-238, a potent and selective dual CECR2/BPTF probe, exhibits IC50 values of 30 nM and 350 nM, respectively. Additionally, it inhibits BRD9 with a pIC50 of 5.9, demonstrating lesser activity against another 338 kinases [1] [2].

TP-238 hydrochloride is a highly potent and selective dual CECR2/BPTF probe, demonstrating IC50 values of 30 nM and 350 nM, respectively. It additionally exerts inhibitory effects on BRD9, with a pIC50 value of 5.9, while displaying lower activity against 338 other kinases.

NDH-1 inhibitor-1 is an effective NDH-1 inhibitor, which can inhibit bovine SMP (mitochondrial granules), potato SMP and Escherichia coli, with pI50 values of <4, 5.40, 6.15 µM, respectively.

Thioether-cyclized helix B peptide, CHBP (TFA), is the trifluoroacetic (TFA) salt of CHBP, enhancing metabolic stability and exhibiting renoprotective effects by promoting autophagy through inhibition of mTOR C1 and activation of mTOR C2 [1].

Cys-αvβ6-BP TFA is a cysteine-terminated peptide that binds to αvβ6.

αvβ6-BP TFA is a selective αvβ6-binding peptide used for molecular imaging research.

GSK1379725A is a selective BPTF ligand [Kd = 2.8 μM].

DCB29 is a selective inhibitor of the BPTF bromodomain with an IC50 value of 13.2 μM. It is utilized in research for treating diseases related to BPTF, such as bladder cancer, colorectal cancer, melanoma, leukemia, and other cancers.

BI-7190 is a selective BPTF inhibitor with a dissociation constant (Kd) of 3.5 nM. It is applicable in cancer research.

DC-BPi-07 is a selective BPTF inhibitor with an IC50 value of 16.0 nM for BPTF-H4. It is applicable in research related to leukemia.

GSK1379767A is a dual inhibitor of BPTF and Brd4.

DC-BPi-11, a potent inhibitor of the bromodomain PHD finger transcription factor (BPTF), exhibits significant anti-proliferative effects against leukemia cells with an IC50 value of 698 nM.

DC-BPi-11 hydrochloride is a BPTF (bromodomain PHD finger transcription factor) inhibitor with an IC50 value of 698 nM, demonstrating significant anti-proliferative effects on leukemia cells [1].