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Results for "
bmy-25801 hcl
" in TargetMol Product Catalog- Inhibitors & Agonists1
Z-VAE(OMe)-fmk
T715861027141-02-1
Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin's C-terminal tail, thereby occupying the P1' (leaving group) site, a binding site perhaps used by the unknown C-terminal extension of ubiquitin in the actual in vivo substrate(s) of UCHL1.
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