benzenesulfonate

Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.

Propargyl benzenesulfonate is a useful organic compound for research related to life sciences. The catalog number is T124544 and the CAS number is 6165-75-9.

Ivacaftor benzenesulfonate, used for cystic fibrosis treatment, is an orally bioavailable CFTR potentiator.

CE-178253 benzenesulfonate is a CB1 antagonist with activity in the central nervous system.

ERK-IN-3 benzenesulfonate is a potent and orally active inhibitor of ERK . ERK-IN-3 benzenesulfonate inhibits ERK1 2 with low single-digit nM IC 50 values. ERK-IN-3 benzenesulfonate can be used for the research of cancers driven by RAS mutations.

Methyl benzenesulfonate is a useful organic compound for research related to life sciences. The catalog number is T66555 and the CAS number is 80-18-2.

Tetrasodium, 4-(1,10-phenanthrolin-4-yl)benzenesulfonate, ruthenium((II)) (catalog number: T67328) is a valuable organic compound for life sciences research.

T-0902611 benzenesulfonate is a cytomegalovirus replication inhibitor that may be useful in the treatment of cytomegalovirus infections.

Sofinicline benzenesulfonate (ABT 894 benzenesulfonate), a novel agonist of the nicotinic acetylcholine receptor, specifically targets the α4β2 subtype of nAChR (IC 50 =0.1 nM). This compound shows promise in enhancing cognitive functions such as attention, memory, and working memory. It is potentially useful in research pertaining to attention deficit hyperactivity disorder (ADHD).

Benzenesulfonate (sodium) serves as a biomaterial or organic compound suitable for life science research.

DSP-1053, a benzylpiperidine derivative, is a potent serotonin transporter (SERT) inhibitor with a dissociation constant (K_i) of 1.02 nM and exhibits partial agonistic activity at the 5-HT_1A receptor with a K_i of 5.05 nM, indicating its potential as an antidepressant.

Fasnall, a fatty acid synthase (FASN) inhibitor, exhibits an IC50 of 3.71 μM against the human recombinant enzyme. It halts tritiated acetate incorporation into lipids (IC50= 5.84 μM), boosts ceramide levels, and triggers lipid droplet formation in BT474 HER2+ breast cancer cells. Demonstrating antiproliferative effects on various breast cancer cell lines, including non-tumorigenic MCF-10A and tumorigenic MCF-7, MDA-MB-468, BT474, and SK-BR-3, its efficacy is directly linked to FASN expression in vitro. In murine models of HER2+ breast cancer, particularly the MMTV-Neu model, Fasnall significantly reduces tumor volume and extends survival. Furthermore, it enhances the efficacy of carboplatin in vivo, bolstering the objective response rate of stable disease from 25% with carboplatin alone to 88% when paired with Fasnall.

LSD1-IN-7 Methylbenzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.

6-((TERT-BUTOXYCARBONYL)AMINO)HEXYL 4-METHYLBENZENESULFONATE is a useful organic compound for research related to life sciences and the catalog number is T64473.

2-Hydroxyethyl 4-methylbenzenesulfonate is a useful organic compound for research related to life sciences and the catalog number is T64507.

2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-yl 4-methylbenzenesulfonate is a useful organic compound for research related to life sciences and the catalog number is T64637.

2-(2-(((Benzyloxy)carbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate is a useful organic compound for research related to life sciences and the catalog number is T64702.

((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate is a pharmaceutical intermediate used in the synthesis of posaconazole with anticancer activity.

Benzyl 2-(2-aminoacetamido)acetate 4-methylbenzenesulfonate, catalog number T65216 and CAS number 1738-82-5, is a valuable organic compound for life sciences research.

(Tosylazanediyl)bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) is a useful organic compound for research related to life sciences. The catalog number is T65339 and the CAS number is 16695-22-0.

5-((tert-Butoxycarbonyl)amino)pentyl 4-methylbenzenesulfonate is a useful organic compound for research related to life sciences and the catalog number is T65454.

(R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is a useful organic compound for research related to life sciences. The catalog number is T65902 and the CAS number is 219823-47-9.

(S)-2-Hydroxyethyl 2-amino-3-methylbutanoate 4-methylbenzenesulfonate is a useful organic compound for research related to life sciences and the catalog number is T66579.

Dibenzyl 2-aminosuccinate 4-methylbenzenesulfonate is a useful organic compound for research related to life sciences and the catalog number is T66781.