benzenesulfonate

Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.

Ivacaftor benzenesulfonate, used for cystic fibrosis treatment, is an orally bioavailable CFTR potentiator.

(R)-Indeloxazine benzenesulfonate (AS1069562) is an orally active inhibitor of serotonin (5-HT) and norepinephrine (NE) reuptake, with IC50 values of 0.35 μM and 3.3 μM, respectively. It exhibits analgesic activity and can enhance neurological function by improving neurotrophic support.

ERK-IN-3 benzenesulfonate is a potent and orally active inhibitor of ERK . ERK-IN-3 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC 50 values. ERK-IN-3 benzenesulfonate can be used for the research of cancers driven by RAS mutations.

Sofinicline benzenesulfonate (ABT 894 benzenesulfonate), a novel agonist of the nicotinic acetylcholine receptor, specifically targets the α4β2 subtype of nAChR (IC 50 =0.1 nM). This compound shows promise in enhancing cognitive functions such as attention, memory, and working memory. It is potentially useful in research pertaining to attention deficit hyperactivity disorder (ADHD).

Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor with an IC50 of less than 0.5 nM and a Kinact/Ki of 7.69×10^4 M^-1s^-1.

Amlodipine Besylate(Amlodipine benzenesulfonate) is a long-lasting calcium channel blocker.

Mesoridazine Besylate (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine.

CE-178253 benzenesulfonate is a CB1 antagonist with activity in the central nervous system.

Methyl benzenesulfonate is a useful organic compound for research related to life sciences. The catalog number is T66555 and the CAS number is 80-18-2.

Tetrasodium, 4-(1,10-phenanthrolin-4-yl)benzenesulfonate, ruthenium((II)) (catalog number: T67328) is a valuable organic compound for life sciences research.

Benzenesulfonate (sodium) serves as a biomaterial or organic compound suitable for life science research.

Z-Lys-OBzl benzenesulfonate is a biochemical reagent used as a reference compound in the study of succinylated proteins.

2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole benzenesulfonate is a pharmaceutical intermediate employed in the synthesis of various active compounds.

DSP-1053, a benzylpiperidine derivative, is a potent serotonin transporter (SERT) inhibitor with a dissociation constant (K_i) of 1.02 nM and exhibits partial agonistic activity at the 5-HT_1A receptor with a K_i of 5.05 nM, indicating its potential as an antidepressant.

Fasnall, a fatty acid synthase (FASN) inhibitor, exhibits an IC50 of 3.71 μM against the human recombinant enzyme. It halts tritiated acetate incorporation into lipids (IC50= 5.84 μM), boosts ceramide levels, and triggers lipid droplet formation in BT474 HER2+ breast cancer cells. Demonstrating antiproliferative effects on various breast cancer cell lines, including non-tumorigenic MCF-10A and tumorigenic MCF-7, MDA-MB-468, BT474, and SK-BR-3, its efficacy is directly linked to FASN expression in vitro. In murine models of HER2+ breast cancer, particularly the MMTV-Neu model, Fasnall significantly reduces tumor volume and extends survival. Furthermore, it enhances the efficacy of carboplatin in vivo, bolstering the objective response rate of stable disease from 25% with carboplatin alone to 88% when paired with Fasnall.

4-Phenyl-4-piperidinecarboxylic acid 4-methyl-benzenesulfonate ,with CAS No. 83949-32-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Phenyl-4-piperidinecarboxylic acid 4-methyl-benzenesulfonate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Propargyl benzenesulfonate is a useful organic compound for research related to life sciences. The catalog number is T124544 and the CAS number is 6165-75-9.

T-0902611 benzenesulfonate is a highly specialized synthetic small molecule target the human liver X receptor α and β isoforms with exceptional binding affinity and selectivity, activation of downstream target genes such as ABCA1 and APOE across various preclinical experimental models to modulate cholesterol efflux and lipid metabolism within specialized research environments.

Ethyl Benzenesulfonate (Standard) is a reference standard of Ethyl Benzenesulfonate intended for quantitative analysis, quality control, and related biochemical research applications.

Isopropyl benzenesulfonate (Isopropyl besylate) is a sulfonate ester that is also considered a potential genotoxic impurity.

Sodium 3-nitrobenzenesulfonate is a mild oxidant. Sodium 3-nitrobenzenesulfonate can protect the shade when fabrics are printed or steamed in pad dyeing and counteract the effect of reducing substances.

LSD1-IN-7 Methylbenzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.

4-Aminobutyl 4-methylbenzenesulfonate is a PROTAC linker (PROTAClinker) used in the synthesis of PROTACs, such as PROTAC BRD4 Degrader-32.