azide c2 azide

Azide-C2-Azide, a cleavable linker crucial in ADC (Antibody-Drug Conjugate) synthesis, joins cytotoxic drugs to antibodies, enabling precise delivery to target cells or proteins. Its cleavable nature ensures controlled drug release, optimizing the effectiveness of ADCs.

Bromo-PEG1-C2-azide, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Ald-C2-PEG4-azide is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Azide-C2-SS-C2-biotin is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Boc-N-Amido-PEG2-C2-azide is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Bromo-PEG2-C2-azide is a non-cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

N-Boc-N-bis(C2-PEG1-azide) is an alkyl ether-based PROTAC linker suitable for synthesizing PROTACs [1].

NH-bis(C2-PEG1-azide) is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Ald-Ph-amido-C2-PEG3-azide, a PEG-based linker for PROTACs, joins two essential ligands necessary for forming PROTAC molecules and facilitates selective protein degradation via the ubiquitin-proteasome system within cells.

AZD-CO-C2-Ph-amido-Ph-azide is an alkyl chain-derived PROTAC linker suitable for the synthesis of PROTACs [1].

Pomalidomide-C2-amide-C5-azidea, a derivative of pomalidomide, can be used to synthesize an efficient PROTAC molecule targeting CDK9 and enhances antiproliferative activity [1].

HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-like PROTAC linker that can be used to synthesize PROTAC molecules, and also contains a DBCO moiety for click chemistry with azide groups.