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Results for "

atx/lpa

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    5
    TargetMol | Inhibitors_Agonists
CRT0273750
CRT 0273750, CRT-0273750
T311011979939-16-6
CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM.
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Z-HA155
CS-963
T115331312201-00-5
Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.
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TargetMol | Inhibitor Sale
PAT-347
T702751689554-51-5
PAT-347 is a potent Autotaxin Inhibitor. Autotaxin (ATX) is a secreted enzyme responsible for the hydrolysis of lysophosphatidylcholine (LPC) to the bioactive lysophosphatidic acid (LPA) and choline. The ATX-LPA signaling pathway is implicated in cell survival, migration, and proliferation; thus, the inhibition of ATX is a recognized therapeutic target for a number of diseases including fibrotic diseases, cancer, and inflammation, among others.
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10-14 weeks
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PAT-347 sodium
PAT-347,PAT347,PAT 347
T28300
PAT-347 is a potent inhibitor of Autotaxin (ATX), a secreted enzyme responsible for the hydrolysis of lysophosphatidylcholine (LPC) to the bioactive lysophosphatidic acid (LPA) and choline.
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BI-2545
T145602162961-71-7
BI-2545 is an autotaxin (ATX) inhibitor that significantly reduces LPA. For human ATX and rat ATX, the IC50s values are 2.2 nM and 3.4 nM , respectively.
    7-10 days
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