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Results for "

asn 002

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
NPD-039
T697652229043-40-5
NPD-039 is an inhibitor of trypanosoma brucei phosphodiesterase B1 (TbrPDEB1).
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6-8 weeks
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Gusacitinib
ASN-002
T143311425381-60-7
Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).
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TargetMol | Inhibitor Sale
Gusacitinib HCl
T697662228989-14-6
Gusacitinib, also known as ASN-002 and EN-3351, is a potent dual inhibitor of SYK JAK kinases. ASN002 showed strong antitumor activity in both hematological and solid tumor xenograft models. ASN002 strongly suppressed the SYK and JAK family kinase signaling pathways as measured in pLAT and pSTAT assays, respectively. When profiled in a panel of 178 cell lines, ASN002 showed strong anti-proliferative activity in many lymphoid leukemia cell lines, including SU-DHL-6, SU-DHL-4, OCI-LY10, H929 and Pfeiffer.
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1-2 weeks
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