ape 1

APE1-IN-1 is a potent inhibitor of purine pyrimidine endonuclease 1 (APE1) that crosses the blood-brain barrier, exhibits potential antitumor activity, and enhances the cytotoxicity of the alkylating agent [methyl methanesulfonate] on cancer cells.

CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.

Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).

APE-IN-1 can be used for the early diagnosis and drug research of Alzheimer's disease. APE-IN-1 is a potent Asparagine endopeptidase (AEP) inhibitor with IC 50 value of 89 nM [1].

Anthopleurin-C (APE 2-1) is a cardiotonic polypeptide that exhibits a potent positive inotropic effect [1].