20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T61683 | Antiparasitic agent-9 | ||
Antiparasitic agent-9 (compound 47) is a highly active and orally administered antiparasitic agent, exhibiting potent antiparasitic efficacy against the human parasite [1]. | |||
T83025 | Antiparasitic agent-19 | ||
Antiparasitic Agent-19 (Compound 40) is a broad-spectrum antiparasitic with minimal toxicity to Trypanosoma brucei, Leishmania infantum, and Trypanosoma cruzi [1]. | |||
T61160 | Antiparasitic agent-2 | ||
Antiparasitic agent-2 (compound 8a) exhibits potent antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi), with IC50s of 7.28 μM and 2.30 μM, respectively. Additionally, it dem... | |||
T83024 | Antiparasitic agent-20 | Parasite | |
Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T. brucei and T. cruzi with EC50 values of 0.09 µM and 14.1 µM, respectively [1]. | |||
T79415 | Antiparasitic agent-18 | Parasite | |
Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T. brucei (EC 50 =0.4 µM), T. cruzi (EC 50 =0.21 µM), and L. donovani (EC 50 =0.26 µM) [1]. | |||
T61538 | Antiparasitic agent-10 | ||
Antiparasitic agent-10 (Compound 94) is a potent anti-parasitic agent specifically designed to target and combat parasitic infections. It demonstrates notable anti-schistosomal activity, particularly against adults of Sc... | |||
T61221 | Antiparasitic agent-8 | ||
Antiparasitic agent-8 (Compound 9) exhibits potent antiparasitic activity against Hymenolepis nana, while demonstrating low levels of cytotoxicity [1]. | |||
T61245 | Antiparasitic agent-7 | ||
Antiparasitic agent-7 (compound 5d) displays specific antiparasitic activity against Leishmania infantum (L. infantum), exhibiting an IC50 value of 2.85 μM. Additionally, Antiparasitic agent-7 demonstrates cytotoxicity a... | |||
T74773 | Antiparasitic agent-14 | ||
Antiparasitic Agent-14 is a potent antiparasitic compound with demonstrated cytotoxicity and antiparasitic activity, effectively inhibiting the growth of trypomastigote and amastigote forms [1]. | |||
T61001 | Antiparasitic agent-6 | ||
Antiparasitic agent-6 (compound 5b) shows selectively antiparasitic activity against Leishmania infantum (L. infantum) (IC 50 = 3.89 μM). Antiparasitic agent-6 also exhibits certain cytotoxicity against HepG2 with a CC50... | |||
T60519 | Antiparasitic agent-4 | ||
Antiparasitic agent-4 (compound 4q) exhibits high antiparasitic activity with IC50 of 8.51 μM for Leishmania infantum (L. infantum) and IC50 of 2.20 μM for Trypanosoma cruzi ( T. cruzi ). Antiparasitic agent-4 is also cy... | |||
T61641 | Antiparasitic agent-5 | ||
Antiparasitic agent-5 (compound 8h) exhibits potent selectivity as an antiparasitic agent against Leishmania infantum (L. infantum), with an IC50 value of 2.50 μM. Additionally, this compound displays cytotoxic effects o... | |||
T78966 | Antiparasitic agent-17 | Parasite | |
Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-resistant (PfK1) strains, with IC50 values of 0.96 μM and 1.67 μM, ... | |||
T5471 | GUANABENZ | Adrenergic Receptor | |
GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist. | |||
T21957 | Guanabenz hydrochloride | NE56490 | Adrenergic Receptor |
Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects. | |||
T7093 | Rafoxanide | CDK , Parasite | |
Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations. | |||
T6275 | Obatoclax Mesylate | Obatoclax,GX15-070 | BCL , Parasite , Autophagy |
Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3. | |||
T5S0018 | Betulonic acid | (+)-Betulonic acid,Betunolic acid,Liquidambaric acid | Parasite , HSV |
1. Betulonic acid (Liquidambaric acid) amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative characteristics, wh... | |||
T10328 | Anti-parasitic agent 3 | Others | |
Anti-parasitic agent 3 is an anti-parasitic agent active against drug-resistant parasites. | |||
T2160 | Suramin Sodium Salt | BAY-205,Suramin hexasodium salt,NF-060 | Apoptosis , Phosphatase , SARS-CoV , Sirtuin , Reverse Transcriptase , Topoisomerase , Parasite |
Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f... |