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Search Results for " antiparasitic "

20

Compounds

Cat No. Product Name Synonyms Targets
T61683 Antiparasitic agent-9
Antiparasitic agent-9 (compound 47) is a highly active and orally administered antiparasitic agent, exhibiting potent antiparasitic efficacy against the human parasite [1].
T83025 Antiparasitic agent-19
Antiparasitic Agent-19 (Compound 40) is a broad-spectrum antiparasitic with minimal toxicity to Trypanosoma brucei, Leishmania infantum, and Trypanosoma cruzi [1].
T61160 Antiparasitic agent-2
Antiparasitic agent-2 (compound 8a) exhibits potent antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi), with IC50s of 7.28 μM and 2.30 μM, respectively. Additionally, it dem...
T83024 Antiparasitic agent-20 Parasite
Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T. brucei and T. cruzi with EC50 values of 0.09 µM and 14.1 µM, respectively [1].
T79415 Antiparasitic agent-18 Parasite
Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T. brucei (EC 50 =0.4 µM), T. cruzi (EC 50 =0.21 µM), and L. donovani (EC 50 =0.26 µM) [1].
T61538 Antiparasitic agent-10
Antiparasitic agent-10 (Compound 94) is a potent anti-parasitic agent specifically designed to target and combat parasitic infections. It demonstrates notable anti-schistosomal activity, particularly against adults of Sc...
T61221 Antiparasitic agent-8
Antiparasitic agent-8 (Compound 9) exhibits potent antiparasitic activity against Hymenolepis nana, while demonstrating low levels of cytotoxicity [1].
T61245 Antiparasitic agent-7
Antiparasitic agent-7 (compound 5d) displays specific antiparasitic activity against Leishmania infantum (L. infantum), exhibiting an IC50 value of 2.85 μM. Additionally, Antiparasitic agent-7 demonstrates cytotoxicity a...
T74773 Antiparasitic agent-14
Antiparasitic Agent-14 is a potent antiparasitic compound with demonstrated cytotoxicity and antiparasitic activity, effectively inhibiting the growth of trypomastigote and amastigote forms [1].
T61001 Antiparasitic agent-6
Antiparasitic agent-6 (compound 5b) shows selectively antiparasitic activity against Leishmania infantum (L. infantum) (IC 50 = 3.89 μM). Antiparasitic agent-6 also exhibits certain cytotoxicity against HepG2 with a CC50...
T60519 Antiparasitic agent-4
Antiparasitic agent-4 (compound 4q) exhibits high antiparasitic activity with IC50 of 8.51 μM for Leishmania infantum (L. infantum) and IC50 of 2.20 μM for Trypanosoma cruzi ( T. cruzi ). Antiparasitic agent-4 is also cy...
T61641 Antiparasitic agent-5
Antiparasitic agent-5 (compound 8h) exhibits potent selectivity as an antiparasitic agent against Leishmania infantum (L. infantum), with an IC50 value of 2.50 μM. Additionally, this compound displays cytotoxic effects o...
T78966 Antiparasitic agent-17 Parasite
Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-resistant (PfK1) strains, with IC50 values of 0.96 μM and 1.67 μM, ...
T5471 GUANABENZ Adrenergic Receptor
GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist.
T21957 Guanabenz hydrochloride NE56490 Adrenergic Receptor
Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects.
T7093 Rafoxanide CDK , Parasite
Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.
T6275 Obatoclax Mesylate Obatoclax,GX15-070 BCL , Parasite , Autophagy
Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.
T5S0018 Betulonic acid (+)-Betulonic acid,Betunolic acid,Liquidambaric acid Parasite , HSV
1. Betulonic acid (Liquidambaric acid) amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative characteristics, wh...
T10328 Anti-parasitic agent 3 Others
Anti-parasitic agent 3 is an anti-parasitic agent active against drug-resistant parasites.
T2160 Suramin Sodium Salt BAY-205,Suramin hexasodium salt,NF-060 Apoptosis , Phosphatase , SARS-CoV , Sirtuin , Reverse Transcriptase , Topoisomerase , Parasite
Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f...
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