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T.cruzi-IN-4
🥰Excellent
Catalog No. T210285
T.cruzi-IN-4 (Compound 21) is an antiparasitic agent. It suppresses both the trypomastigote and amastigote forms of Trypanosoma cruzi, achieving an IC50 of 0.033 μM (after 120 hours). Additionally, T.cruzi-IN-4 hinders the promastigote and amastigote forms of Leishmania infantum, with IC50 values of 28.74 and 61.82 μM respectively, and it inhibits the promastigote form of Leishmania amazonensis with an IC50 of 18.38 μM.
T.cruzi-IN-4
T.cruzi-IN-4
🥰Excellent
Catalog No. T210285
T.cruzi-IN-4 (Compound 21) is an antiparasitic agent. It suppresses both the trypomastigote and amastigote forms of Trypanosoma cruzi, achieving an IC50 of 0.033 μM (after 120 hours). Additionally, T.cruzi-IN-4 hinders the promastigote and amastigote forms of Leishmania infantum, with IC50 values of 28.74 and 61.82 μM respectively, and it inhibits the promastigote form of Leishmania amazonensis with an IC50 of 18.38 μM.
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Product Introduction
Bioactivity
Chemical Properties
| Description | T.cruzi-IN-4 (Compound 21) is an antiparasitic agent. It suppresses both the trypomastigote and amastigote forms of Trypanosoma cruzi, achieving an IC50 of 0.033 μM (after 120 hours). Additionally, T.cruzi-IN-4 hinders the promastigote and amastigote forms of Leishmania infantum, with IC50 values of 28.74 and 61.82 μM respectively, and it inhibits the promastigote form of Leishmania amazonensis with an IC50 of 18.38 μM. |
| Formula | C13H9N5O4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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