anti-tigit

Vibostolimab is a monoclonal antibody against T cell immune proteins and the ITIM domain.Vibostolimab has shown anti-tumor activity in in vitro trials and can be used to study non-small cell lung cancer (NSCLC) and melanoma.

Anti-Mouse TIGIT Antibody (1G9) is an IgG1, κ antibody inhibitor derived from mice, specifically targeting mouse TIGIT.

Tiragolumab(MTIG-7192A) is a monoclonal antibody that targets T-cell immunoglobulin and the ITIM structural domain (TIGIT).Tiragolumab is often used in combination with the PD-L1 inhibitor, Atezolizumab, for the treatment of solid malignant tumors such as non-small cell lung cancer.

Belrestotug (EOS-448), an antagonistic anti-TIGIT (VSIG9, VSTM3) antibody of the human immunoglobulin G1 kappa (hIgG1 kappa) class, exhibits antineoplastic activity [1].

Rilvegostomig is a bispecific humanized IgG1 antibody targeting the immune-regulating receptor programmed cell death protein 1 (PD-1) and the co-inhibitory immune checkpoint molecule T cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT). It enhances T cell activation, fostering a robust anti-tumor immune response, especially in cancers such as non-small cell lung cancer (NSCLC). Molecular weight: 146.06 KD.