act-35

OX40 TNFRSF4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.7 kDa and the accession number is P43489.

OX40 TNFRSF4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.34 kDa and the accession number is NP_003318.1.

OX40 TNFRSF4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.9 kDa and the accession number is P43489.

OX40 TNFRSF4 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 48.69 kDa and the accession number is NP_003318.1.

OX40 TNFRSF4 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.1 kDa and the accession number is B1ASL3.

OX40 TNFRSF4 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 47.3 kDa and the accession number is B1ASL3.

OX40 TNFRSF4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.3 kDa and the accession number is B1ASL3.

Expression system: E. coli
Length: 35-140, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-314, Full Length
Activity: Cell Activity

SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has been demonstrated to inhibit the activity of certain serine proteases, such as cathepsin G found in neutrophils, and chymases present in mast cells, by inducing a major conformational rearrangement, and thus protects some tissues from damage caused by proteolytic enzymes. This enzyme is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease, and mutations of this gene have been observed in patients with Parkinson disease and chronic obstructive pulmonary disease. Besides, ACT gene polymorphism has been implicated with Alzheimer's disease (AD), cerebral amyloid angiopathy (CAA), as well as stroke, since SerpinA3 is a major constituent of the plaques in AD and an inhibitor of amyloid beta peptide degradation.

Expression system: E. coli
Length: 35-161, Partial
Activity: Not Tested