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Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C, with Kds of 2.7, 20, 0.14, and 6 nM, respectively.

Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.

Tripterin (Celastrol) is a natural product, a proteasome inhibitor that inhibits the pancreatic rennet-like activity of the 20S proteasome (IC50=2.5 μM). Tripterin has anti-inflammatory, anti-infectious, and immunomodulatory properties.

Anti-Mouse IL-2 Antibody (S4B6-1) is a monoclonal inhibitory antibody targeting mouse interleukin-2. It can reduce the level of CD4+ T cells, upregulate the proportion of regulatory T cells (Tregs), and induce Th17 cell differentiation. It is suitable for mechanism studies related to tumors such as melanoma.

EU-102 is a human monoclonal antibody (mAb) targeting TNFSF18. It is applicable for research in the field of solid tumors.

Anti-ERBB3/HER3 (SGP1) is a human monoclonal antibody (mAb) targeting ERBB3/HER3. It inhibits Neuregulin-stimulated growth of cultured breast cancer cells and can be utilized in breast cancer research.

SAR-439459 is a human monoclonal antibody (mAb) targeting TGFB1/TGFβ-1. It blocks TGFβ-mediated pSMAD signaling and inhibits T cell and NK cell activity. Additionally, SAR-439459 exhibits antitumor properties.

TQC2731 is a fully human monoclonal antibody that targets TSLP. It can be utilized for research on asthma and other related diseases mediated by Th2 inflammation.

VDJ001 is a high-affinity humanized anti-IL-6R monoclonal antibody. It is applicable for research in rheumatoid arthritis.

AGEN1307 is a human monoclonal antibody (mAb) targeting TIGIT. It features an active FcγR binding region, enhancing antibody-dependent cellular cytotoxicity (ADCC). AGEN1307 is utilized in cancer research.

TGTB227 is a human monoclonal antibody (mAb) targeting TIGIT. It works by reducing Foxp3 expression in regulatory T cells (Tregs), thereby inhibiting their immunosuppressive function. TGTB227 is applicable for research in tumor immunology.

GSK2800528 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa, utilized for research related to inflammation and psoriasis.

AMP-224 is a fusion protein that targets PD-L2 and can specifically bind to PD-1T cells (long-term stimulated/exhausted T cells). It is applicable in research on colorectal cancer and solid tumors.

MK-1248 is a human IgG4 monoclonal antibody (mAb) targeting TNFSF18. It enhances the proliferative response of tumor-infiltrating lymphocytes to anti-CD3 stimulation and promotes the production of anti-tumor associated regulatory cytokines. MK-1248 is utilized in research on solid tumors.

GR-28 is an inhibitor of the small C-terminal domain phosphatase 1 (SCP1). It suppresses the transcriptional activity of the repressor element 1-silencing transcription factor (REST) and inhibits the proliferation of glioblastoma cells, with IC50 values of 2.9 and 10.1 µM for cell lines A172 and T98G, respectively.