Tetrapeptide-1

Tetrapeptide-1, a bioactive peptide known for its antioxidant properties, is frequently cited as an ingredient in cosmetics [1].

Acetyl tetrapeptide-15 Acetate (Skinasensyl Acetate), a synthetic peptide used in cosmetic products for sensitive skin, is an endomorphin-2 derivative that extends the range of neuronal excitability thresholds in the μ-opioid receptor via an endorphin-like pathway, and can be used to study inflammatory and neuropathic pain produced by skin hyperreactivity. Inflammatory and neuropathic pain produced by skin hyperresponsiveness.

Myristoyl Tetrapeptide-12 Acetate (Myristoyl Tetrapeptide-12 Acetate (959610-24-3 Free base)) , the reaction product of myristic acid and Tetrapeptide-12, is a peptide stimulating hair and eyelash growth and enhancing the appearance of eyelashes and or eyebrows. Myristoyl tetrapeptide-12 can increase keratinocyte proliferation improve appearance, firmness elasticity, and skin thickness.

Palmitoyl tetrapeptide-10 is a bioactive peptide known for its anti-aging properties, reportedly utilized as an ingredient in cosmetics [1].

Tetrapeptide-11 is the reaction product of Acetic Acid and tetrapeptide-11, containing leucine, proline, and tyrosine residues. It boosts cell growth, Syndecan-1, and Collagen XVII synthesis. Tetrapeptide-11 has a face and body anti-wrinkle and anti-aging

Acetyl tetrapeptide-15 targets neuro sensitive skin which by decreasing the release of pro-inflammatory mediators.

Ac-YVAD-CHO (L 709049) is a selective and potent tetrapeptide interleukin 1β-converting enzyme (ICE) and caspase-1 (ICE)-like protease inhibitor with anti-inflammatory activity, inhibits cancer cell growth, and inhibits the production of mature IL-lβ. Ac-YVAD-CHO attenuates quinolinic acid-induced p53 increase and apoptosis in rat striatum.

Acth (1-4) is the ACTH N-terminal tetrapeptide.

Acth (1-4) acetate is the ACTH N-terminal tetrapeptide.

Bilaid C is a tetrapeptide μ-opioid receptor agonist (Ki= 210 nM in HEK293 cell membranes expressing the human receptor) that has been found inPenicillium.1It inhibits forskolin-induced cAMP accumulation by 77% in HEK293 cells expressing the human μ-opioid receptor when used at a concentration of 10 μM. Bilaid C induces inward rectifying potassium channel (Kir) currents in rat locus coeruleus slices that endogenously express high levels of the μ-opioid receptor (EC50= 4.2 μM). 1.Dekan, Z., Sianati, S., Yousuf, A., et al.A tetrapeptide class of biased analgesics from an Australian fungus targets the μ-opioid receptorProc. Natl. Acad. Sci. USA116(44)22353-22358(2019)

ND1-YL2 is a peptide-based PROTAC®Degrader of steroid receptor co-activator 1 (SRC-1; also known as nuclear receptor coactivator 1, NCOA1). ND1-YL2 is composed of a stapled peptide that binds SRC-1 (YL2) joined by a linker to a tetrapeptide that binds UBR box domains. Upon ternary complex formation, SRC-1 is polyubiquitinated and subsequently degraded via the N-degron pathway. This Degrader induces dose-dependent degradation of SRC-1 in the MDA-MB-231 triple negative breast cancer cell line (DC50 = 10 μM), and binds to the PAS-B domain of SRC-1 (Ki = 320 nM). ND1-YL2 inhibits MDA-MB-231 cell migrationin vitro, and suppresses metastasis of MDA-MB-231 cellsin vivo.

Z-VRPR-FMK (TFA), a selective and irreversible inhibitor of Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), is a tetrapeptide shown to provide protection against influenza A virus (IAV) infection [1].

Tyr-W-MIF-1, an opioid tetrapeptide, exhibits both opiate and antiopiate activities, and has been demonstrated to induce analgesia [1] [2] [5].

AGPV, a tetrapeptide, demonstrates potential in preventing schistosome parasite infections, according to research [1].

AGPV TFA, a tetrapeptide, demonstrates potential for schistosome parasite infection prevention research [1].

Tetrapeptide-30, a skin-brightening peptide comprised of four amino acids, functions as a tyrosinase inhibitor. It effectively lightens hyperpigmentation and evens skin tone by decreasing tyrosinase levels and preventing melanocyte activation [1].

Antiulcer Agent 2, a tetrapeptide comprising aspartic acid, alanine, histidine, and lysine, localizes at the N-terminal of human albumin. This compound shows promise in treating ulcers and producing active oxygen [1] [2].

H-Leu-Trp-Met-Arg-OH, a tetrapeptide, serves as a substrate for studies on aminopeptidase-mediated hydrolysis [1].

Goralatide, a natural tetrapeptide, acts as a physiological regulator of hematopoiesis and has been shown to inhibit the proliferation of primitive hematopoietic cells [1].

Tetrapeptide, an α-MSH analogue, stimulates melanin production and mitigates DNA damage by attenuating reactive oxidative species generation and augmenting DNA photoproduct repair [1].

Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a selective and potent proteasome inhibitor, with inhibition constants (Ki) of 1.5 µM for branched-chain amino acid-preferred, 2.3 µM for small neutral amino acid-preferred, and 40.5 µM for chymotrypsin-like activities, and an inhibitory concentration (IC50) of 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity [1].

Val-Gly-Ser-Glu (NSC 350591), an ECF-A tetrapeptide, dose-dependently enhances the rosetting of human eosinophils with complement-coated sheep erythrocytes (EAC3b) without affecting neutrophils [1].

Tetrapeptide-4 is a peptide commonly incorporated into skincare formulations for its anti-aging benefits, which include diminishing wrinkles and fortifying collagen, elastin, and fibronectin [1].

Tetrapeptide-26, a bioactive peptide, is known for its anti-aging properties and is reportedly utilized as an ingredient in cosmetics [1].