T7621

6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.

POT-4 TFA (AL-78898A TFA), a derivative of Compstatin, efficiently inhibits the activation of complement factor C3 and is utilized in research related to age-related macular degeneration [1] [2].

[Asp5]-Oxytocin acetate is a neurohypophyseal hormone analogue positioned at the 5-position, noted for its significant biological activity. It stimulates uterine contractions in vitro, an effect that is amplified by the presence of Mg 2+. Furthermore, this compound exhibits rat uteroconstrictor, avian vasodilator, and rat antidiuretic capabilities.

B 9430 is a potent bradykinin B1/B2 receptor antagonist [1].

HXR9 hydrochloride, a cell-permeable peptide and competitive antagonist of the HOX/PBX interaction, selectively reduces cell proliferation and induces apoptosis in cells with elevated HOXA/PBX3 gene expression, notably MLL-rearranged leukemic cells [1] [2] [3]. By inhibiting the interaction between HOX proteins and the transcription factor PBX, which associates with HOX proteins in paralogue groups 1 to 8, it disrupts a critical regulatory mechanism in these cells.

5′-Nucleotidase (CD73), an ectoenzyme and intrinsic membrane glycoprotein, catalyzes the hydrolysis of 5-nucleotides into their corresponding nucleosides [1].

KRpep-2d, a potent inhibitor of K-Ras, effectively suppresses the proliferation of cancer cells driven by K-Ras. This compound is suitable for use in cancer research [1].

KRpep-2d (TFA) is a potent K-Ras inhibitor that effectively impedes the proliferation of K-Ras-driven cancer cells, making it a valuable asset for cancer research [1].

Lonodelestat TFA (POL6014 TFA) is a potent and selective peptide inhibitor of human neutrophil elastase (hNE) with demonstrated oral activity, showing promise for cystic fibrosis (CF) research [1] [2] [3].

Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 exhibits serum stability and is non-toxic to neuronal cells, selectively inhibiting tau fibrillization over Aβ 42.

Peptide 46 is a short peptide that inhibits SC-dependent DNA synthesis by targeting the bacterial sliding clamp (SC).

MDP1, derived from Melittin, disrupts the membrane integrity of both Gram-positive and Gram-negative bacteria, leading to bacterial death through membrane damage. This compound exhibits potent antibacterial activity against multidrug-resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa [1].

MDP1 acetate, a derivative of Melittin, compromises membrane integrity of both Gram-positive and Gram-negative bacteria leading to bacterial death through membrane damage. MDP1 acetate exhibits antibacterial activity against multidrug-resistant and reference strains of S. aureus, E. coli, and P. aeruginosa. MDP1 acetate is used in antimicrobial membrane biology research systems to investigate peptide-induced membrane disruption, bacterial permeability changes, and antimicrobial peptide mechanism profiling.