1,2 dilauroyl sn glycero 3 phosphocholine

DLPC is an LRH-1 agonist ligand. DLPC is a phospholipid for biological study[1][2].

1,2-DLPC-d9 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d9) is a deuterium-labeled version of 1,2-DLPC. The compound 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) serves as a ligand for LRH-1 agonists and is utilized as a phospholipid in liposome synthesis. In adipocytes, 1,2-DLPC promotes lipolysis and apoptosis via a TNFα-dependent pathway. Additionally, it attenuates palmitate-induced insulin resistance in muscle cells through inflammation mediated by PPARα.

1,2-DLPC-d55 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d55) is a deuterium-labeled variant of 1,2-DLPC. The compound 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) serves as a ligand for the LRH-1 agonist and is a phospholipid utilized in the synthesis of liposomes. It enhances fat cell lipolysis and apoptosis through a TNFα-dependent pathway, while also inhibiting palmitate-induced insulin resistance by modulating muscle cell inflammation via the PPARα pathway.

1,2-DLPC-d46 (1,2-Dilauroyl-sn-glycero-3-phosphocholine-d46) is a deuterium-labeled variant of 1,2-DLPC. The compound 1,2-DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) acts as a ligand for the LRH-1 agonist and is utilized as a phospholipid in the synthesis of liposomes. It enhances adipocyte lipolysis and apoptosis through the TNFα-dependent pathway and mitigates palmitate-induced insulin resistance by inhibiting inflammation in myocytes via the PPARα-mediated pathway.

(S)-1,2-Dilauroyl-sn-glycero-3-phosphocholine is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.