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Podocarpaceae

Podocarpaceae is a large family of mainly Southern Hemisphere conifers, comprising about 156 species of evergreen trees and shrubs. Podocarpus neriifolius D. Don (Podocarpaceae) is a tree growing in south Asian countries. While the wood of this plant is used as timber for furniture and in paper-making, its edible fruits are consumed raw or cooked, and decoctions from its leaves are used in folk medicine to relieve rheumatism and painful joints. Plants of the genus Podocarpus have been reported to exhibit a variety of biological activities ranging from plant-growth regulation to antibacterial and antiproliferative effects.

  • Secoisolariciresinol
    TN219729388-59-8
    Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes.
    • $129
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  • Podocarpusflavone A
    TQ013422136-74-9
    Podocarpusflavone A is a DNA topoisomerase I inhibitor with moderate anti-proliferative activity that induces cell apoptosis in MCF-7.
    • $81
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  • Prunin
    Naringenin 7-0-glucoside
    TN2111529-55-5
    Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can stimulate growth of Pseudomonas aeruginosa and different Bacilllus sp. Prunin exhibits a markedly enhanced solubility compared to naringenin and naringin while maintaining the in vitro inhibition of HMG-CoA reductase.
    • $116
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  • Totarol
    (+)-Totarol
    TN2279511-15-9
    Totarol ((+)-Totarol) shows antibacterial effects against several pathogenic Gram-positive bacteria, mycobacterium tuberculosis.
    • $40
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  • 9,13-Epidioxy-8(14)-abieten-18-oic acid
    T51575309-35-3
    9,13β-Epidioxy-8(14)-abieten-18-oic acid has anti-inflammatory activities, it exhibits moderate activities on NO levels in LPS-stimulated murine microglia BV2 cells, with IC50 values of 57.3 ± 0.2 uM. It is also a potential antitumor-promoting diterpenoid, it shows potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate. 9 α ,13 β -Epidioxyabeit-8(14)en-18-oic acid may contribute to the growth inhibitory effect of the pine needles and may play an important role in the allelopathy of red pine.
    • $620
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  • Nagilactone C
    TN462324338-53-2
    Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation. Nagilactone C shows high insecticidal activity against second-instar nymphs of Eocanthecona furcellata. Nagilactone C possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 microg/ml, respectively.
    • $708
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  • 2,3-Dihydroamentoflavone 7,4'-dimethyl ether
    TN2695873999-88-3
    2,3-Dihydroamentoflavone 7,4'-dimethyl ether exhibits cytotoxicity (ED50 values < 4 microg/mL) against P-388 and HT-29 cell lines in vitro.
    • $740
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  • 2,3-Dihydroheveaflavone
    TN2696110382-42-8
    2,3-Dihydroheveaflavone is a natural product for research related to life sciences. The catalog number is TN2696 and the CAS number is 110382-42-8.
    • $740
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  • 4beta-Carboxy-19-nortotarol
    TN306955102-39-1
    4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/ NADH, it inhibits linoleic acid autoxidation but not generation of superoxide anion.
    • $540
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  • 5,5'-Dimethoxysecoisolariciresinol
    TN30791002106-91-3
    5,5'-Dimethoxysecoisolariciresinol is a natural product from Podocarpus spicata.
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  • 2,3-dihydrosciadopitysin
    TN270034421-19-7
    2,3-dihydrosciadopitysin is a natural product of Podocarpus, Podocarpaceae. The catalog number is TN2700 and the CAS number is 34421-19-7. 2,3-dihydrosciadopitysin can be used as a reference standard.
    • $590
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  • 2,3-Dihydropodocarpusflavone A
    TN2699852875-96-8
    2,3-Dihydropodocarpusflavone A (Catalog Number: TN2699, CAS: 852875-96-8) is a natural product used in life sciences research.
    • $670
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