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Araucariales

Araucariales is an order of gymnosperms that includes ancient conifer families such as Araucariaceae and Podocarpaceae, distributed mainly in the Southern Hemisphere. Members produce diterpenoids, resin acids, and lignans that contribute to their long-term ecological resilience. In biomedical research, Araucariales is studied for its antimicrobial, anti-inflammatory, and cytotoxic activities, though it is less explored than other conifers. Its ancient evolutionary lineage makes it valuable for understanding early gymnosperm diversification and resin-based chemical defense systems.

  • Secoisolariciresinol
    TN219729388-59-8
    Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes.
    • $129
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  • Podocarpusflavone A
    TQ013422136-74-9
    Podocarpusflavone A is a DNA topoisomerase I inhibitor with moderate anti-proliferative activity that induces cell apoptosis in MCF-7.
    • $81
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  • Prunin
    Naringenin 7-0-glucoside
    TN2111529-55-5
    Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can stimulate growth of Pseudomonas aeruginosa and different Bacilllus sp. Prunin exhibits a markedly enhanced solubility compared to naringenin and naringin while maintaining the in vitro inhibition of HMG-CoA reductase.
    • $116
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  • Totarol
    (+)-Totarol
    TN2279511-15-9
    Totarol ((+)-Totarol) shows antibacterial effects against several pathogenic Gram-positive bacteria, mycobacterium tuberculosis.
    • $40
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  • Isocupressic acid
    (+)-Isocupressic acid
    TN42771909-91-7
    Isocupressic acid ((+)-Isocupressic acid) is an abortifacient isolated from pine needles and bark that blocks progesterone production in bovine corpus luteum cells.
    • $677
    7-10 days
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  • 9,13-Epidioxy-8(14)-abieten-18-oic acid
    T51575309-35-3
    9,13β-Epidioxy-8(14)-abieten-18-oic acid has anti-inflammatory activities, it exhibits moderate activities on NO levels in LPS-stimulated murine microglia BV2 cells, with IC50 values of 57.3 ± 0.2 uM. It is also a potential antitumor-promoting diterpenoid, it shows potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate. 9 α ,13 β -Epidioxyabeit-8(14)en-18-oic acid may contribute to the growth inhibitory effect of the pine needles and may play an important role in the allelopathy of red pine.
    • $620
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  • Acetylisocupressic acid
    TN334352992-82-2
    Acetylisocupressic acid is a natural product of Araucaria, Araucariaceae. The catalog number is TN3343 and the CAS number is 52992-82-2. Acetylisocupressic acid can be used as a reference standard.
    • $520
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  • Nagilactone C
    TN462324338-53-2
    Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation. Nagilactone C shows high insecticidal activity against second-instar nymphs of Eocanthecona furcellata. Nagilactone C possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 microg/ml, respectively.
    • $708
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  • 2,3-Dihydroamentoflavone 7,4'-dimethyl ether
    TN2695873999-88-3
    2,3-Dihydroamentoflavone 7,4'-dimethyl ether exhibits cytotoxicity (ED50 values < 4 microg/mL) against P-388 and HT-29 cell lines in vitro.
    • $740
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  • 2,3-Dihydroheveaflavone
    TN2696110382-42-8
    2,3-Dihydroheveaflavone is a natural product for research related to life sciences. The catalog number is TN2696 and the CAS number is 110382-42-8.
    • $740
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  • 4beta-Carboxy-19-nortotarol
    TN306955102-39-1
    4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/ NADH, it inhibits linoleic acid autoxidation but not generation of superoxide anion.
    • $540
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  • 5,5'-Dimethoxysecoisolariciresinol
    TN30791002106-91-3
    5,5'-Dimethoxysecoisolariciresinol is a natural product from Podocarpus spicata.
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  • 2,3-dihydrosciadopitysin
    TN270034421-19-7
    2,3-dihydrosciadopitysin is a natural product of Podocarpus, Podocarpaceae. The catalog number is TN2700 and the CAS number is 34421-19-7. 2,3-dihydrosciadopitysin can be used as a reference standard.
    • $590
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  • 2,3-Dihydropodocarpusflavone A
    TN2699852875-96-8
    2,3-Dihydropodocarpusflavone A (Catalog Number: TN2699, CAS: 852875-96-8) is a natural product used in life sciences research.
    • $670
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