Melia

Azadirachtin has antifungal activity, used as an insecticide.

1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin is an effective insecticide for Ae.

5,7,3'-Trihydroxy-4'-methoxy-8-prenylflavanone, a flavonoid, is found in the bark of *Azadirachta indica*.

3,5-Dimethoxybenzoic acid is a benzoic acid derivative exhibiting antifungal activity against A. rabiei, suitable for biochemical experiments and drug synthesis research.

1-Deacetylnimbolinin B is a natural product from Melia toosendan Sieb. et Zucc.

3-Epicabraleahydroxylactone has anti-tumor promoting effect, it has anti-carcinogenic activity by the inhibitory effect on the induction of Epstein-Barr virus early antigen(EBV-EA) by the tumor promoter.

Meliasenin B may cause hepatotoxicity, it displays dose-dependent toxicity on HepG2 cells.

Odoratone shows insecticidal activities, it shows mortality on fourth instar larvae of mosquitoes (Anopheles stephensi) with LC(50) values of 154 ppm. Odoratone exhibits strong antifeedant activity against Pieris brassicae.

3-Epimeliasenin B is a natural product for research related to life sciences. The catalog number is TN5953 and the CAS number is 1222475-77-5.

Deacetylnimbin shows significant insecticidal activity to Plutella xylostlla L.and Piers rapae L.

Kulactone has cytotoxic effects, with IC50 values of 5.6-21.2ug/mL, it inhibited (ED(50) 2.5-6.2 microg/mL) the P388 cancer cell line.

2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits cathepsin-mediated pro-survival signaling which resulted in growth arrest of TNBC cells.

Ohchinin acetate is a natural product from Melia azedarach.

2,3-Dihydro-3α-methoxynimbolide induces apoptosis via both mitochondrial and death receptor pathways in stomach (AZ521) cancer cell line.

Deacetylsalannin shows antifeedant activity against Reticulitermes speratus Kolbe (95% protective concentration or PC95 = 1373.1 ug/disc).

3-Epiturraeanthin is a natural product for research related to life sciences. The catalog number is TN2932 and the CAS number is 22415-24-3.

Meliasendanin D is a natural product from Melia toosendan.

1,3-Diacetylvilasinin shows marginal cytotoxicities against certain human tumor cell lines. It also shows antifeeding activity towards insects.

Kulinone has cytotoxic effects, with IC50 values of 5.6-21.2 ug/mL, it inhibited (ED(50) 2.5-6.2 microg/mL) the P388 cancer cell line.

Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect

Sendanolactone possesses moderate cytotoxic activity against KB cell lines.

Ohchinin exhibits potent inhibitory activities with 26 - 66% reduction of melanin content at 100 μm concentration with almost no or low toxicity to the B16 melanoma cells (70 - 99% cell viability at 100 μm).