Meliaceae

Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells.

Azadirachtin B (Deacetylazadirachtinol) is a terpenoid compound isolated from Azadirachta seeds, with insecticidal, anticancer, anti-inflammatory, antitumor, and antiviral activities, useful in the study of viral infections. Azadirachtin B also has osteoblast proliferation, differentiation, and mineralization properties.

Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally active cathepsin inhibitor. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases[1][2].

Azadirachtin has antifungal activity, used as an insecticide.

Isoscoparin is derived from Gentiana algida Pall with antioxidant and anti-adipogenic activities. Isoscoparin can be used in stuides about the prevention and treatment of obesity.

Aurantiamide has anti-cancer, anti-inflammatory and antinociceptive activities, it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimulation through its inhibition of the

1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin is an effective insecticide for Ae.

ß-Thujaplicinol, a hydroxylated thujaplicinone isolated from western red cedar heartwood, has antiviral activity, inhibits hepatitis B virus replication by blocking viral ribonuclease H activity, and can be used in the study of viral infections.

4',7-Di-O-methylnaringenin (4',7-Di-O-methylnaringenin) is a natural product.

Dimethyl phthalate (Fermine) has many uses, including in solid rocket propellants, plastics, and insect repellants. Acute (short-term) exposure to dimethyl phthalate, via inhalation in humans and animals, results in irritation of the eyes, nose, and throat. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of dimethyl phthalate in humans. Animal studies have reported slight effects on growth and on the kidney from chronic oral exposure to the chemical. EPA has classified dimethyl phthalate as a Group D, not classifiable as to human carcinogenicity.

5,7,3'-Trihydroxy-4'-methoxy-8-prenylflavanone, a flavonoid, is found in the bark of *Azadirachta indica*.

Cedrelone is a citrulline analog and a phenazine biosynthesis-like domain protein (PBLD) activator.Cedrelone induces apoptosis in cancer cells.Cedrelone is a very potent inducer of apoptosis, causing cell cycle arrest.Cedrelone has insecticidal activity, inhibiting the growth of arrowhead venom of P. saucia and inhibiting moulting of the milkweed bug (Oncopeltus fasciatus). Cedrelone has insecticidal activity, inhibiting the growth of P. saucia and inhibiting moulting of the milkweed bug (Oncopeltus fasciatus).Cedrelone has antitumor effects and exhibits significant cytotoxicity against cancer cell lines such as -60, SMMC-7721, A-549, MCF-7, and SW480.Cedrelone is a very potent inducer of apoptosis, causing cell cycle arrest.Cedrelone is a very potent inducer of apoptosis, leading to cell cycle arrest.

1,4-Androstadiene-3,17-dione exhibits inhibitory activity against aromatase and tyrosinase, and can be used in biochemical experiments and drug synthesis.

3,5-Dimethoxybenzoic acid is a benzoic acid derivative exhibiting antifungal activity against A. rabiei, suitable for biochemical experiments and drug synthesis research.

(+)-Rocaglamide is a natural alkaloid, widely used in biochemical experiments and drug synthesis research.

Richenoic acid is a natural product of Walsura, Meliaceae. The catalog number is TN4912 and the CAS number is 134476-74-7. Richenoic acid can be used as a reference standard.

1-Deacetylnimbolinin B is a natural product from Melia toosendan Sieb. et Zucc.

C-3'-Methoxyrocaglamide has insecticidal activity.

3-Epicabraleahydroxylactone has anti-tumor promoting effect, it has anti-carcinogenic activity by the inhibitory effect on the induction of Epstein-Barr virus early antigen(EBV-EA) by the tumor promoter.

3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone is a cytotoxic tirucallane C26 triterpenoid that has been extracted from the stem barks of Aphanamixis grandifolia.

Meliasenin B may cause hepatotoxicity, it displays dose-dependent toxicity on HepG2 cells.

Isoscoparin-2′′O-glucoside is a natural flavonoid exhibiting antioxidant activity.

Aglain B is a natural product of Aglaia, Meliaceae. The catalog number is TN3359 and the CAS number is 177262-32-7. Aglain B can be used as a reference standard.

Walsuralactam A in the formula I, which is used as an active ingredient, and is used for treating and preventing the tumour.