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TargetMol | Tags Natural Product Categories

Juglans

TargetMol offers a curated selection of compounds derived from the Juglans genus and maintains a collection of over 25,000 high-purity natural products and natural product monomer reference standards (sourced from plants, microorganisms, marine organisms, and animals). Utilizing a refined classification system that covers multi-dimensional information such as genus, family, biological activity, and structural types, our products feature clear source information and standardized data, making them suitable for reference standard research, high-throughput screening, virtual screening, and drug discovery studies.

  • Juglone
    Regianin, 5-Hydroxy-1,4-naphthoquinone
    T4010481-39-0
    Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.
    • $41
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    TargetMol | Citations Cited
  • Regiolone
    (-)-Isosclerone
    TN4903137494-04-3
    Regiolone is a naphthoquinone natural product with phytotoxic properties. In in vitro studies, Regiolone exhibits antiproliferative activity in tumor cells and can induce apoptosis in MCF-7 breast cancer cells.
    • $815
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