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Natural Product Categories Natural Product Categories Juglandaceae
Juglandaceae is a plant family known as the walnut family, containing 7–10 genera and 50 species. All parts of a walnut tree is known to be used in traditional medicine including the roots and leaves for treating diabetes, rheumatism, fever and skin diseases and haemorrhoids. Walnut oil and other products are also common ingredients of dry skin creams, anti-wrinkle and anti-ageing products formulations. Walnuts are an admirable source of nutrients and phytochemicals which are of great benefit for human health, such as polyphenols, proteins, fibers, sterols, and essential fatty acids. Considering only the levels of phenolic antioxidants, walnut is the most enriched among nut species.
- beta-Amyroneβ-AmyronTN3500638-97-1beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity.
- $122
SizeQTY - EngeletinDihydrokaempferol 3-rhamnosideT6S0840572-31-61. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
- $41
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Cited - JugloneRegianin, 5-Hydroxy-1,4-naphthoquinoneT4010481-39-0Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.
- $41
SizeQTY Cited - Regiolone(-)-IsoscleroneTN4903137494-04-3Regiolone is a naphthoquinone natural product with phytotoxic properties. In in vitro studies, Regiolone exhibits antiproliferative activity in tumor cells and can induce apoptosis in MCF-7 breast cancer cells.
- $815
SizeQTY - PixinolT81452162062-88-6Pixinol is a natural glycoside compound that exhibits cytotoxic effects on human lung carcinoma GLC4 and adenocarcinoma COLO 320 cell lines, with IC50 values of 71 µM and 43 µM, respectively. Pixinol is utilized in cancer cell biology research focused on cytotoxicity profiling, tumor cell susceptibility assessment, and natural product–derived compound screening in lung and colorectal carcinoma model systems.
- $195
SizeQTY - 28-Demethyl-β-amyrone28-Demethyl-beta-amyroneTN123173493-60-428-Demethyl-beta-amyrone is a natural product
- $250
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