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Natural Product Categories Natural Product Categories Dioscoreales
Dioscoreales is an order of monocot flowering plants that includes families such as Dioscoreaceae, containing yams and related tuber-forming plants. Members of this order are rich in steroidal saponins, alkaloids, and polysaccharides. In biomedical research, Dioscoreales is highly significant due to diosgenin and related compounds, which serve as key precursors for synthetic steroid drugs. The order is also studied for its anti-inflammatory, anticancer, and metabolic regulatory effects, as well as its importance in nutritional and functional food research.
- Daucosterolβ-Sitosterol β-D-glucoside, Sitogluside, Eleutheroside A, AlexandrinT3871474-58-8Daucosterol (Sitogluside) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol(β-Sitosterol β-D-glucoside) has efficient and inexpensive neuroprotectant effect, to contribute to IGF1-like activity, could be potentially developed as a medicine for ischemic stroke treatment.
- $41
SizeQTY - DioscinCollettiside III, CCRIS 4123T647319057-60-4Dioscin (Collettiside III) is a saponin with antitumor activities.
- $30
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Cited - ProtodioscinFurostanol IT232155056-80-9Protodioscin (Furostanol I) is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.
- $30
SizeQTY - GracillinT377419083-00-2Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new drugs against I. multifiliis.
- $30
SizeQTY Cited - Methyl protodioscinSmilax saponin B, NSC-698790T377154522-52-0Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in human A549 cells is closely associated with Mitochondrial membrane potential, caspase-3, and mitochondrial cytochrome c.
- $30
SizeQTY - DiosgeninNitogeninT2867512-04-9Diosgenin (Nitogenin) is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.
- $30
SizeQTY Cited - YamogeninT7529512-06-1Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.
- $48
SizeQTY - PseudoprotodioscinT5S0246102115-79-71. Pseudoprotodioscin has moderate cytotoxicity.
- $35
SizeQTY - Batatasin IVTN244460347-67-3Batatasin IV is identified from Dioscorea opposita which is a a type of homologous medicinal plant and is commonly used as food in daily life.
- $130
SizeQTY - 8-Epidiosbulbin E acetateTN134291095-48-68-Epidiosbulbin E acetate is a abundant furan compound found in Dioscorea bulbifera L., exhibiting broad-spectrum plasmid elimination activity against multidrug-resistant bacteria, and can be used to induce liver injury models in mice.
- $52
SizeQTY - DeltoninT384455659-75-1Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).
- $98
SizeQTY - Taccalonolide ATN2254108885-68-3Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects,with cytotoxic and antimalarial activities. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells.
- $48
SizeQTY - ProtogracillinT2S174954848-30-5Protogracillin, a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW), may inhibit platelet aggregation (PAG) and thrombosis, potentially reducing the risk of cardiovascular diseases through its anti-thrombotic action.
- $60
SizeQTY - Diosbulbin BT4S079020086-06-01. Diosbulbin B exhibits potential hepatotoxicity. 2. Diosbulbin B has potential anti-tumor effects which may be related to influencing the immune system for the first time.
- $35
SizeQTY - PseudoprotogracillinT2S0250637349-03-2Pseudoprotogracillin is a steroidal saponin extracted from Dioscoreae.
- $282
SizeQTY - Methyl protogracillinTJS174854522-53-1Methyl protogracillin is a natural product from Dioscorea collettii var. hypoglauca with anti-cancer activity.
- $132
SizeQTY - DihydropinosylvinTN386114531-52-3Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum, it also exhibits strong antibacterial activity against Bacillus cereus, S
- $30
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- Taccalonolide BTN2256108885-69-4Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.
- $48
SizeQTY - Taccafurostanoside ATN8256290809-76-6Taccafurostanoside A is a pentacyclic steroidal compound used in life science research.
- $460
SizeQTY - Taccalonolide AJTN22551349904-82-0Taccalonolide AJ is a microtubule stabilizer; it has excellent and highly persistent antitumor efficacy when administered directly to the tumor, suggesting that the lack of antitumor efficacy seen with systemic administration of AJ is likely due to its sh
- $290
SizeQTY - Batatasin ITN243851415-00-0Batatasin I, a natural product from Dioscorea batatas, is a [chemical compound] used for eye research. It is a [useful compound] because it has structural and [chemical properties] ideal for making synthetic antibiotics.
- $1,768
SizeQTY - Diosbulbin DTN387266756-57-8Diosbulbin D shows direct toxic effect on hepatocytes, the mechanism could be associated with oxidative stress.
- $1,910
SizeQTY - Diosbulbin JTN38731187951-06-9Diosbulbin J is a natural product for research related to life sciences. The catalog number is TN3873 and the CAS number is 1187951-06-9.
- $660
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