Derris

Rotenone is a natural plant-derived insecticide that acts as an inhibitor of mitochondrial electron transport chain complex I. It promotes the generation of mitochondrial reactive oxygen species, induces apoptosis, and is commonly used to establish Parkinson's disease models.

Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.

Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.

3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 nM, respectively. 3'-Methoxydaidzein was specific for collagen-induced platelet aggregation with IC50 values of 12.3 and 61.5µM, respectively. 3'-Methoxydaidzein acts as an analgesic by inhibiting voltage-gated sodium channels. 3'-Methoxydaidzein showed antioxidant activity and antiplatelet aggregation activity.

Anhydroglycinol is a natural product found in the stems of Lespedeza homoloba with antioxidant activity.

Alpha-Toxicarol is a rotenoid with anticancer and insecticidal activities. It induces oxidative stress and mitochondrial dysfunction, used for natural product and cytotoxicity research.

12-Deoxo-12alpha-acetoxyelliptone is a natural product from Derris robusta.

6alpha-Hydroxymedicarpin is a natural product for research related to life sciences. The catalog number is TN3200 and the CAS number is 61135-92-0.

Pterocarpadiol B is a kind of very rare 6a,11b-dihydroxypterocarpan, and its presence as a marker may be helpful in chemotaxonomical classification.

Auriculasin is a natural product of Derris, Fabaceae. The catalog number is TN3471 and the CAS number is 60297-37-2. Auriculasin can be used as a reference standard.

Isochandalone is a natural product from Derris robusta.

1,11b-Dihydro-11b-hydroxymaackiain is a natural product from Derris robusta.

Dehydrotoxicarol is a natural product of Derris, Fabaceae. The catalog number is TN3811 and the CAS number is 59086-93-0. Dehydrotoxicarol can be used as a reference standard.

3-Hydroxy-8,9-methylenedioxypterocarpene is a natural product for research related to life sciences. The catalog number is TN2944 and the CAS number is 59901-98-3.

6alpha-Hydroxymaackiain is a natural product from Derris robusta.

Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production. Lasiodiplodin inhibits electron transport chain.

Pterocarpadiol D is a kind of very rare 6a,11b-dihydroxypterocarpan, and its presence as a marker may be helpful in chemotaxonomical classification.

1,11b-Dihydro-11b-hydroxymedicarpin is a natural product from Derris robusta.

Pterocarpadiol C is a kind of very rare 6a,11b-dihydroxypterocarpan, and its presence as a marker may be helpful in chemotaxonomical classification.

11-Hydroxytephrosin inhibits NF-kappaB activity.

Pterocarpadiol A is a kind of very rare 6a,11b-dihydroxypterocarpan, and its presence as a marker may be helpful in chemotaxonomical classification.

Glycinol enhances osteogenic differentiation and attenuates the effects of age on mesenchymal stem cells, it could as a potential preventive or treatment for osteoporosis. Glycinol also has antidiuretic activity.

Warangalone is an anti-malarial compound that inhibits the growth of Plasmodium falciparum strains 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with IC50 values of 4.8 μg/mL and 3.7 μg/mL, respectively.

Derrisisoflavone B is a natural product from Derris robusta.