Cynanchum

Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.

Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Qingyangshengenin B has antiepileptic and anti-aging effects, it can extend lifespan, increase heat stress-resistance, delay body paralysis, and increase the chemotaxis response in C. elegans models of Alzheimer's disease. Otophylloside B can suppress the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.

Qingyangshengenin (Cynanchagenin) is a steroid used in the preparation of antiepileptic agents.

2,3-Dihydroxy-4-methoxyacetophenone (2',3'-Dihydroxy-4'-methoxyacetophenone) is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease.

2'-Hydroxy-5'-methoxyacetophenone (5-Methoxy-2-hydroxyacetophenone) is an active biochemical.

Otophylloside O is a natural progestin glycoside that inhibits the growth of cancer cells such as HepG2, HeLa, and U251 at micromolar concentrations (IC50 = 36.21–58.25 μM), demonstrating cytotoxic and anticancer potential.

Otophylloside F can suppress the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.

Glaucoside C is a natural product for research related to life sciences. The catalog number is TN6466 and the CAS number is 81474-89-7.

Glaucoside A is a natural product for research related to life sciences. The catalog number is TN6465 and the CAS number is 81474-91-1.

Cynatratoside A and Cynanversicoside C are therefore potential candidate drugs for use against Ichthyophthirius multifiliis.

Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.

Glaucogenin C mono-D-thevetoside is a natural product from Cynanchum stauntonii.

Qingyangshengenin A is a C-21 steroidal glycoside isolated from Cynanchum otophyllum and has been shown to possess antiepileptic activity.

Clemaphenol A is a natural product from Cynanchum auriculatum.