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Brachypterum

TargetMol offers a curated selection of compounds derived from the Brachypterum genus and maintains a collection of over 25,000 high-purity natural products and natural product monomer reference standards (sourced from plants, microorganisms, marine organisms, and animals). Utilizing a refined classification system that covers multi-dimensional information such as genus, family, biological activity, and structural types, our products feature clear source information and standardized data, making them suitable for reference standard research, high-throughput screening, virtual screening, and drug discovery studies.

  • Rubone
    2'-Hydroxy-2,4,4',5,6'-pentamethoxychalcone
    T2474473694-15-2
    Rubone (2'-Hydroxy-2,4,4',5,6'-pentamethoxychalcone), a natural product and a modulator of miR-34a (microRNA-34), upregulates miR-34a expression in a p53-dependent manner, which in turn downregulates the expression of downstream targets Bcl-2, cyclin-D1, CDK6, SIRT1, and FOXP1, thereby inhibiting tumor growth and reversal of hepatocellular carcinoma (HCC) and chemoresistance in prostate cancer.
    • $52
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