Welcome to our new website experience

As we continue to roll out more enhancements, enjoy a host of updated features to make your journey with us smarter, faster and easier.

What's new

Intuitive search with relevant results
Easily compare products in detail
Quick, simple checkout
Be part of our community, read or submit product reviews

We would love to know what you think, so we have included a feedback tab on every page.

Popular Searches

Wikimole

1Erastin
2MRTX1133
3BI-2493
4Azelaprag
5Trastuzumab

New Product

1Vamikibart
2Remtolumab
3Evunzekibart
4ABBV-706
5Ilepatril TFA

Compound Library

1Covalent Inhibitor Library
2Ion Channel Targeted Library
3Autophagy Compound Library
4EMA Approved Drug Library
5Anti-Cancer Metabolism Compound Library

Home

All

Inhibitors & Agonists

Compound Libraries

Focused Bioactive Libraries
Natural Product Libraries
Fragment Libraries
Drug-like Compound Libraries
Natural Products
Recombinant Proteins
Inhibitory Antibodies
Antibody-drug Conjugate/ADC Related
Popular product application
Detection Antibody
Peptides
PROTAC
Dyes
Reagent Kits
Molecular and Cellular Research
Disease Modeling
Reference Standards
Technical Services

Autophagy
Cell Cycle/Checkpoint
Cytoskeletal Signaling
Chromatin/Epigenetic
Endocrinology/Hormones
Hedgehog/Smoothened
Angiogenesis
DNA Damage/DNA Repair
Apoptosis
NF-κB
Neuroscience
MAPK
Microbiology/Virology
GPCR/G Protein
TGF-beta/Smad
Immunology/Inflammation
Proteases/Proteasome
Stem Cells
Ubiquitination
Oxidation-Reduction
Membrane transporter/Ion channel
PI3K/Akt/mTOR signaling
Metabolism
Wnt/beta-catenin
JAK/STAT signaling
Tyrosine Kinase/Adaptors
TLR
PARP
Focused Bioactive Libraries Approved Drug Library FDA-Approved Drug Library FDA-Approved & Pharmacopeia Drug Library Clinical Compound Library Preclinical Compound Library Bioactive Compound Library Target-Focused Phenotypic Screening Library ReFRAME Related Library Epigenetics Compound Library Cytoskeletal Signaling Pathway Compound Library Transcription Factor-Targeted Compound Library GPCR Compound Library Ion Channel Inhibitor Library Endocrinology-Hormone Compound Library JAK-STAT Compound Library NF-κB Signaling Compound Library DNA Damage & Repair Compound Library Ubiquitination Compound Library Ferroptosis Compound Library Cuproptosis Compound Library Kinase Inhibitor Library Anti-Cancer Compound Library Anti-Bacterial Compound Library Anti-Cardiovascular Disease Compound Library CNS-Penetrant Compound Library Anti-Viral Compound Library Anti-Neurodegenerative Disease Compound Library Peptide Compound Library
Natural Product Libraries Natural Product Library for HTS Natural Product Library Human Endogenous Metabolite Library Human Endogenous Metabolite Compound Library Plus Natural Product Derivatives Library Polyphenolic Natural Product Library Alkaloid Natural Product Library Flavonoid Natural Product Library Terpene Natural Product Library Covalent Natural Product Library The Yao nationality medicine Library Tibetan medicine Compound Library Traditional Mongolian Medicine Compound Library Food as Medicine Compound Library Marine Natural Product Library Microbial Natural Product Library Anti-infective Natural Product Library Anti-Tumor Natural Product Library Anti-Inflammatory Traditional Chinese Medicine Compound Library Anti-COVID-19 Traditional Chinese Medicine Compound Library Anti-virus Traditional Chinese Medicine Monomer Library Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library PBCRBS Traditional Chinese Medicine Compound Library Traditional Chinese Medicine Monomer Library Selected Plant-Sourced Compound Library Gut Microbial Metabolite Library Selectable Natural Product Library Natural Product Derivatives Library for CADD
Fragment Libraries High Solubility Fragment Library Drug-Fragment Library
Drug-like Compound Libraries Mini Scaffold Library Golden Scaffold Library Covalent Inhibitor Library
Steroids
Coumarins
Lignans
Saccharides and Glycosides
Alkaloids
Terpenoids
Phenylpropanoids
Flavonoids
Phenols
Quinones
Others
CAR-T Therapy Target Proteins
CD Proteins
Complement System
Cytokines and Growth Factors
Enzymes
Fluorescent Proteins
Hormones
Immune Checkpoint Proteins
Others
Receptor Proteins
Viral Proteins
Biosimilar Antibody
Anti-Mouse/Rat In Vivo Antibody
Research Antibody
Bispecific Antibody
Isotype Control Antibody
Antibody-Drug Conjugate (ADC)
ADC Naked Antibody
Agonist Antibody
Virus Neutralizing Antibody
Fusion Protein
Functional Protein
ADC Antibody
ADC Cytotoxin
ADC Linker
Antibody-Drug Conjugates (ADCs)
Drug-Linker Conjugates for ADC
PROTAC-Linker Conjugates for PAC
Tumor/Cancer
Immune and Inflammatory
Neurodegenerative Diseases
Endocrine and Metabolism
Cardiovascular Diseases
Infectious Diseases
Organoids and Stem Cells
Primary antibodies
Flow cytometry antibodies
Monoclonal Antibodies
Loading Control Antibodies
Tag Antibodies
Fluorescent Antibodies
Polyclonal Antibodies
Recombinant Antibody
Small Molecule Compound Antibody
Phosphorylation Antibody
Methylation/Acetylation Antibody
Secondary Antibodies
Semaglutide
GsMTx4 TFA (1209500-46-8 free base)
Aprotinin
β-Amyloid (1-42), acetate (human)
Insulin (human)
740 Y-P
Ceruletide
Gastrin I, human
Exendin-4
Pam3CSK4 TFA (112208-00-1 free base)
Liraglutide
ATTECs
AUTACs
E3 Ligase Ligand-Linker Conjugate
Ligand for E3 Ligase
Ligands for Target Protein for PROTAC
LYTACs
Molecular Glues
PROTAC Linker
PROTACs
SNIPERs
Target Protein Ligand-Linker Conjugate
Cell biology dyes
Molecular biology dyes
Biological dyes
Fluorescence wavelength dye
Enzyme substrate dyes
Biochemical colorimetric reagent
Chemical analysis
Colorants
Laser dye
Other dyes
Cell Proliferation/Cytotoxicity Assay Kit
Protease Inhibitor Cocktail
Phosphatase Inhibitor Cocktail
Protease and Phosphatase Inhibitor Cocktail
Deacetylase Inhibitor Cocktail
RIPA Lysis Buffer
BCA Protein Quantification Kit
Sterile Antibiotic Solution
SYBR Green qPCR Master Mix
Immunoprecipitation Magnetic Beads
Immunoprecipitation Kits
Protein Purification Magnetic Beads
Agarose Beads
Streptavidin Magnetic Beads
Cell Isolation Kits
Preactivated Magnetic Beads
Polymer Magnetic Beads
Agarose Magnetic Beads
Dextran Magnetic Beads
Oligo (dT) Magnetic Beads
Non-fluorescent Dyes
Cell-associated Fluorescent Dyes
Energy Metabolism Kit
Carbohydrate Metabolism Kit
Nitrogen Metabolism Kit
Lipid Metabolism Kit
Redox Related Kit
Enzyme Activity Assay Kit
Plant Physiological Kit
Elemental/Environmental Reagent Kit
Isotope products
Deuterium Labeled Compounds
Carbon-13 Labeled Compounds
Nitrogen-15 Labeled Compounds
Biochemical Buffers and Solution Reagents
Biomaterials Related Reagents
Biomacromolecule Related Reagents
Cell and Microbial Research Reagents
Natural Bioactive Protein
Other Scientific Research Reagents
Cancer Modeling
Immunology and Inflammation Disease Modeling
Nervous System Disease Modeling
Endocrinology and Metabolism Disease Modeling
Urinary System Disease Modeling
Respiratory System Disease Modeling
Digestive System Disease Modeling
Skin Disease Modeling
Genetically Engineered Disease Modeling
Other Disease Modeling
Cardiovascular System Disease Modeling
Natural Product Standards
Active Small Molecule Standards
Isotope Standards
Peptide Standards
Dye Reagents Standards
Other Standards
Molecular Docking
Virtual Screening
Biomolecular Interaction
Custom Synthesis
AI-driven Ultra High-throughput Virtual Screening
PDBbind+
Molecular Binding & Interaction Assay
GPCR Bioassay
Pharmacokinetics (PK)
Target Fishing

Inhibitors & Agonists

Angiogenesis
Apoptosis
Autophagy
Cell Cycle/Checkpoint
Chromatin/Epigenetic
Cytoskeletal Signaling
DNA Damage/DNA Repair
Endocrinology/Hormones
GPCR/G Protein
Immunology/Inflammation
JAK/STAT signaling
MAPK
Membrane transporter/Ion channel
Metabolism
Microbiology/Virology
Neuroscience
NF-Κb
Others
Oxidation-Reduction
PI3K/Akt/mTOR signaling
PROTAC
Proteases/Proteasome
Stem Cells
Tyrosine Kinase/Adaptors
Ubiquitination
Antibody-drug Conjugate/ADC Related

ALK
Bcr-Abl
BTK
EGFR
FAK
FGFR
FLT
HER
HIF
JAK
PDGFR
Src
Syk
VDA
VEGFR
Apoptosis
ASK
BCL
Caspase
c-RET
DAPK
Fas/FasL
Ferroptosis
FKBP
FOXO1
IAP
Mdm2
Necroptosis
OXPHOS
p53
PD-1/PD-L1
PERK
Pyroptosis
RIP kinase
Survivin
TNF
Autophagy
CXCR
FKBP
LRRK2
lysosomal autophagy
Mitophagy
Antifolate
APC
Aurora Kinase
BMI-1
CDK
Cell Cycle Arrest
Chk
c-Myc
DHFR
DNA/RNA Synthesis
DUB
DYRK
Haspin Kinase
IRE1
KSP
LIM Kinase
Nucleoside Antimetabolite/Analog
PD-1/PD-L1
PLK
Rho
ROCK
Serine/threonin kinase
Wee1
AMPK
Aurora Kinase
DNA Methyltransferase
Epigenetic Reader Domain
HDAC
HIF
HIF/HIF Prolyl-Hydroxylase
Histone Acetyltransferase
Histone Demethylase
Histone Methyltransferase
HuR
JAK
Methionine Adenosyltransferase (MAT)
PAD
PARP
Pim
PKC
Sirtuin
Akt
Arp2/3 Complex
Bcr-Abl
Dynamin
FAK
Gap Junction Protein
HSP
Integrin
Kinesin
Microtubule Associated
Myosin
PAK
PKC
ROCK
Wnt/beta-catenin
ATM/ATR
BMI-1
CRISPR/Cas9
DHFR
DNA
DNA Alkylation
DNA Alkylator/Crosslinker
DNA gyrase
DNA/RNA Synthesis
DNA-PK
DUB
HDAC
MTH1
Nucleoside Antimetabolite/Analog
PARP
PPAR
Sirtuin
Telomerase
Topoisomerase
Androgen Receptor
Aromatase
Estrogen Receptor/ERR
Estrogen/progestogen Receptor
Glucocorticoid Receptor
GPR
LHRH
Opioid Receptor
Oxytocin Receptor
RAAS
Reductase
Thyroid hormone receptor(THR)
5-HT Receptor
Adenosine Receptor
Adiponectin receptor
Adrenergic Receptor
Amylin Receptor
Annexin A
Apelin receptor
Arrestin
Bombesin Receptor
Bradykinin Receptor
cAMP
Cannabinoid Receptor
CaSR
CGRP Receptor
cholecystokinin
CRFR
CXCR
Dopamine Receptor
EBI2/GPR183
Endothelin Receptor
GHSR
Glucagon Receptor
GNRH Receptor
GPCR19
GPR
GRK
GTPase
Guanylate cyclase
Hedgehog/Smoothened
Histamine Receptor
Kisspeptin
Leukotriene Receptor
LPA Receptor
LPL Receptor
Melanin-concentrating Hormone Receptor (MCHR)
Melanocortin Receptor
Melatonin Receptor
Motilin Receptor
Neurokinin receptor
Neuropeptide W
Neuropeptide Y Receptor
Neurotensin Receptor
Opioid Receptor
OX Receptor
Oxytocin Receptor
P2Y Receptor
PACAP
PAFR
Prostaglandin Receptor
Protease-activated Receptor
RXFP receptor
S1P Receptor
SGLT
Sigma receptor
Somatostatin
TSH Receptor
Vasopressin Receptor
AhR
AIM2
Antiviral
Arginase
Aryl Hydrocarbon Receptor
CCR
CD38
CD73
Cell wall
cGAS
Complement System
COX
CXCR
Cytokine release
FKBP
FLAP
Galectin
gp120/CD4
Histamine Receptor
IFNAR
IL Receptor
Immunology/Inflammation related
Interleukin
IRAK
LTR
MALT
MRP
MyD88
NADPH-oxidase
NO Synthase
NOD
NOD-like Receptor (NLR)
NOS
Nrf2
PD-1/PD-L1
PGE Synthase
Prostaglandin Receptor
Pyroptosis
Reactive Oxygen Species
ROS
STING
Thrombopoietin Receptor
TLR
EGFR
HER
JAK
Pim
STAT
ERK
JNK
KLF
KLF
MAPK
MEK
MLK
MNK
p38 MAPK
Raf
S6 Kinase
TOPK
ABC
Anion Exchanger
Aquaporin
ATPase
BCRP
Calcium Channel
CFTR
Chloride channel
CRM1
GABA Receptor
HCN Channel
iGluR
Monoamine Transporter
Monocarboxylate transporter
Na+/Ca2+ Exchanger
Na-K-Cl cotransporter
NPC1L1
OAT
OCT
P2X Receptor
P-gp
Piezo Channel
Potassium Channel
Proton pump
Sodium Channel
TRP/TRPV Channel
VDAC
Acetyl-CoA Carboxylase
aconitase
Acyltransferase
Adenosine deaminase
AhR
Amino Acids and Derivatives
Aminopeptidase
Amylase
Angiotensin-converting Enzyme (ACE)
ATP Citrate Lyase
Calcium Channel
Carbonic Anhydrase
Casein Kinase
CETP
CPT
Decarboxylase
Dehydrogenase
DHFR
Drug Metabolite
Endogenous Metabolite
Epoxide Hydrolase
FAAH
FABP
Factor Xa
Fatty Acid Synthase
FXR
Glucokinase
Glucosidase
Glutathione Peroxidase
Glycosidase
GSNOR
hCE
Hexokinase
HIF/HIF Prolyl-Hydroxylase
HMG-CoA Reductase
HSP
Hydrogenase
Hydroxylase
IDO
Indoleamine 2,3-Dioxygenase (IDO)
Isocitrate Dehydrogenase (IDH)
LDL
Lipase
Lipid
Lipoxygenase
Liver X Receptor
MAGL
MAO
Mitochondrial Metabolism
N-Acetylglucosaminyltransferase
NADPH
NAMPT
NEDD8
Neprilysin
NUDIX hydrolase
P450
PAI-1
PDE
Phosphatase
Phospholipase
Phosphorylase
PKM
PPAR
Procollagen C Proteinase
Prolyl Endopeptidase (PREP)
RAR/RXR
Reactive Oxygen Species
Reductase
Retinoid Receptor
ROR
Serine/threonin kinase
SGK
Stearoyl-CoA Desaturase (SCD)
stilbene oxidase
Taste receptor
Thioredoxin
Transaminase
Transferase
transporter
UGT
Vitamin
Xanthine Oxidase
Antibacterial
Antibiotic
Antifection
Antifungal
Anti-infection
CCR
GluCls
HBV
HCV Protease
HIV Protease
HSV
Influenza Virus
Integrase
Parasite
Reverse Transcriptase
Ribosome
RSV
SARS-CoV
Virus Protease
5-HT Receptor
AAK1 (AP2 associated kinase 1)
AChE
AChR
Adenosine Receptor
Adrenergic Receptor
BACE
Beta Amyloid
Beta-Secretase
CaMK
CGRP Receptor
COX
Dopamine Receptor
FAAH
GABA Receptor
Gamma-secretase
GluR
GlyT
Histamine Receptor
Huntingtin
iGluR
Imidazoline Receptor
MAO
Melanocortin Receptor
Monoamine Oxidase
MT Receptor
Neurokinin receptor
Neuropeptide W
Neuropeptide Y Receptor
NMDAR
NMU2R
Norepinephrine
Opioid Receptor
OX Receptor
P2X Receptor
P2Y Receptor
P-gp
Serotonin Transporter
IRAK
IκB/IKK
NF-κB
NOD
RANKL/RANK
Reactive Oxygen Species
RIP kinase
advanced glycation end products
CYP19A1
Decarboxylase
DprE1
Fer/FerT kinase
Others
Platelet aggregation
Progesterone Receptor
Antioxidant
Free radical scavengers
Glutathione reductase
GPX
GST
Akt
AMPK
ATM/ATR
DNA-PK
GSK-3
MELK
mTOR
PDK
PI3K
PI4K
PTEN
S6 Kinase
SIK
ATTECs
AUTACs
E3 Ligase Ligand-Linker Conjugate
Ligand for E3 Ligase
Ligands for Target Protein for PROTAC
LYTACs
Molecular Glues
PROTAC Linker
PROTACs
SNIPERs
Target Protein Ligand-Linker Conjugate
Carboxypeptidase
Caspase
Cysteine Protease
DPP-4
Gamma-secretase
Glutaminase
HCV Protease
HIV Protease
MMP
Prolyl Endopeptidase (PREP)
Protease
Proteasome
Serine Protease
Thrombin
Tyrosinase
Casein Kinase
Gamma-secretase
GSK-3
Hedgehog/Smoothened
Hippo pathway
JAK
Porcupine
ROCK
Smo
STAT
Stemness kinase
TGF-beta/Smad
Wnt/beta-catenin
YAP
ACK
ALK
Bcr-Abl
BTK
c-Fms
c-Kit
c-Met/HGFR
c-RET
CSF-1R
Discoidin Domain Receptor (DDR)
DYRK
EGFR
Ephrin Receptor
FAK
FGFR
FLT
Hck
HER
IGF-1R
PDGFR
PKA
PYK2
ROS Kinase
Src
Syk
TAM Receptor
Tie-2
Trk receptor
Tyrosine Kinases
VEGFR
DUB
E1/E2/E3 Enzyme
p97
Proteasome
ADC Antibody
ADC Cytotoxin
ADC Linker
Antibody-Drug Conjugates (ADCs)
Drug-Linker Conjugates for ADC
PROTAC-Linker Conjugates for PAC

Compound Libraries

Focused Bioactive Libraries
Natural Product Libraries
Fragment Libraries
Drug-like Compound Libraries
Research Field

General Bioactive Libraries
Approved / Repurposing
Characteristic Bioactive Libraries
Disease Focused
Target / Pathway Focused
Natural Product Derivatives Libraries
Natural Product Library for HTS
Characteristic Natural Product Libraries
TCM Natural Product Library
Activity-classified Natural Product Library
Structure-classified Natural Product Library
Characteristic Fragment Libraries
General Fragment Libraries
Compound Libraries for HTS/HCS
Tumor
Anti-infective
Cardiovascular disease
Development and reproduction
Digestive disorders
Inflammation and immunity
Metabolic diseases
Neurological disorders
Other Fields

Natural Products

Plant
Structure

Other
Alkaloids
Coumarins
Flavonoids
Lignans
Others
Phenols
Phenylpropanoids
Quinones
Saccharides and Glycosides
Steroids
Terpenoids

Recombinant Proteins

CAR-T Therapy Target Proteins
CD Proteins
Complement System
Cytokines and Growth Factors
Enzymes
Fluorescent Proteins
Hormones
Immune Checkpoint Proteins
Others
Receptor Proteins
Viral Proteins

Hematologic Malignancies Target Proteins
Solid Tumors Target Proteins
B Cell CD Proteins
Cell Activation CD Proteins
Cell Adhesion CD Proteins
Cytokine Receptor CD Proteins
Endothelial Cell CD Proteins
Myeloid Cell CD Proteins
NK/Non-lineage Cell CD Proteins
Other CD Proteins
Platelet CD Proteins
T Cell CD Proteins
Cytokines
Epidermal Growth Factor Family, EGFs
Growth Factors
Others
Hydrolases,EC 3
Isomerases,EC 5
Ligases or Synthetases,EC 6
Lyases,EC 4
Oxidoreductases,EC 1
Transferases,EC 2
Translocases,EC 7
Butyrophilins
Co-inhibitory Immune Checkpoint Proteins
Co-stimulatory Immune Checkpoint Proteins
Cell Adhesion Receptors
Cytokines and Growth Factor Receptors
Enzyme-Linked Receptors
Fc Receptors
G Protein-Coupled Receptors, GPCRs
Ion Channel-Linked Receptors
Nuclear Receptors
Receptor Serine/Threonine Kinases
Receptor Tyrosine Kinases
Others
Coronavirus (CoV) Proteins
DENV Proteins
EBOV Proteins
HBV Proteins
HCV Proteins
HIV Proteins
Influenza Proteins
RSV Proteins
Others

Technical Services

CADD & AIDD
Compound Screening

Molecular Docking
Virtual Screening
Biomolecular Interaction
Custom Synthesis
AI-driven Ultra High-throughput Virtual Screening
PDBbind+
Molecular Binding & Interaction Assay
GPCR Bioassay
Pharmacokinetics (PK)
Target Fishing

Topscience Database

Screening Compound Database
Natural Product Database
Bioactive Compound Database
Fragment Compound Database
L1000W Database
Covalent Compound Database
Macrocyclic Compound Database

Knowledge Center

Resources
Product Insights
Latest News

Inhibitors & Agonists

Compound Libraries

Natural Products

Recombinant Proteins

Inhibitory Antibodies

Antibody-drug Conjugate/ADC Related

Brachypterum

Home Natural ProductsSort by SourcePlantaeTracheophytaMagnoliopsidaFabalesFabaceaeBrachypterum

Rubone
2'-Hydroxy-2,4,4',5,6'-pentamethoxychalcone
T2474473694-15-2
Rubone (2'-Hydroxy-2,4,4',5,6'-pentamethoxychalcone), a natural product and a modulator of miR-34a (microRNA-34), upregulates miR-34a expression in a p53-dependent manner, which in turn downregulates the expression of downstream targets Bcl-2, cyclin-D1, CDK6, SIRT1, and FOXP1, thereby inhibiting tumor growth and reversal of hepatocellular carcinoma (HCC) and chemoresistance in prostate cancer.
MicroRNA
- $52
In Stock
Size
QTY
View more