Actaea

23-epi-26-Deoxyactein (27-Deoxyactein) has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affecting activity of the enzyme. It also has anti-cancer activity, it can inhibit growth of the MCF7 human breast cancer cells and induce cell cycle arrest at G1.

Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways involved in lipid disorders and carci

Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia.

Cimigenoside, a constituent of Asclepias, is a γ-secretase inhibitor that inhibits the proliferation or metastasis of human breast cancer cells via the γ-secretase/Notch axis.

DL-Isocitric acid trisodium salt is the protonated form of isocitrate, a substrate in the citric acid cycle. It is useful as a marker for determining the composition of isocitrates in fruit products, including fruit juices.

Cimifugin (Cimitin) inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1, 1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free bioassay system.

Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.

Acetylcimigenol 3-O-alpha-L-arabinopyranoside is an extract derived from Cimicifuga.

Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.

Cimiracemoside D is a natural product derived from [Cimicifuga foetida L.].

Cimicidanol 3-O-alpha-L-arabinoside is a natural product of Cimicifuga, Ranunculaceae. The catalog number is T4S1672 and the CAS number is 161207-05-2. Cimicidanol 3-O-alpha-L-arabinoside can be used as a reference standard.

Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity by decreasing reactive oxygen species (ROS) accumulation and downregulating apoptosis-related Bax/Bcl-2 proteins.

25-Anhydrocimigenol 3-O-beta-D-xyloside has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.

25-O-ethylcimigenol-3-O-beta-D-xylopyranoside has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.

Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may be an effective chemopreventive agen

7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of VCAM-1 expression.

Norkhellol is a natural product for research related to life sciences. The catalog number is TN4669 and the CAS number is 4439-68-3.

Cimigenol is a potential antitumor compound, combination of it with an autophagy inhibitor may be a valuable strategy for the chemoprevention or treatment of colon cancer. It exerted potent cytotoxic activity against SMMC-7721 (7.87μM) and A-549 (12.16 μM

Cimigenol-3-one is a natural product from Calophyllum inophyllum.

Cimicifugoside H2 is a natural product from Cimicifuga foetida.

25-O-methylcimigenol-3-O-beta-D-xylopyranoside is a natural product from Actaea asiatica.

prim-O-Glucosylangelicain is a natural product from Cimicifuga foetida L.

Cimicifugic acid B is a natural product for research related to life sciences. The catalog number is TN3652 and the CAS number is 205114-66-5.

Ebelin lactone is a triterpenoid sapogenin derived from the acid hydrolysis of active saponins (such as bacoside A) found in Bacopa monnieri (Brahmi) and Ziziphus jujuba. Ebelin lactone has been investigated in phytochemical and neuropharmacology-related biochemical research contexts focusing on its formation as a saponin-derived aglycone and its stability and distribution behavior in biological systems. Ebelin lactone is also studied in central nervous system–related receptor interaction models, including systems involving serotonin receptor subtypes such as the 5-HT2A serotonin receptor, for evaluating ligand–receptor binding characteristics and structure–activity relationships relevant to cognitive function–associated signaling pathways in experimental research settings.