Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduce TNF-alpha-induced VCAM-1 expression through regulation o
Cimicifugoside, a triterpenoid isolated from Cimicifuga simplex, is a novel, specific nucleoside transport inhibitor and exhibits immunosuppressive activity.