4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-hydroxylase (DBH) activity and possesses antidepressant activity.

3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.

1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.

Angelicain, also known as Norcimifugin, is a component found in Cimicifuga foetida that exhibits anti-inflammatory activity.

Alloimperatorin (Prangenidin) exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migration. It photosensitizes efficiently the hemolysis of erythrocytes.

Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; it produces a rapid effect mediated by AMPA

Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer

P-Hydroxyphenethyl trans-ferulate exhibits affinity toward 5-HT(7) receptors in a competitive binding assay. P-Hydroxyphenethyl trans-ferulate can double quinone reductase specific activity in Hepa 1c1c7 cells at a level of 2.1 microg/mL (6.6 microM).

1. (+)-(3R,8S)-Falcarindiol is a potential new anticancer agent that exerts its activity through inducing ER stress and apoptosis. 2. Falcarindiol induces immunosuppressive effects in vitro and in vivo and might be a novel therapy for autoimmune or allergic diseases. 3. Falcarindiol has protective effect against CCl(4) toxicity , in part, be explained by anti-lipid peroxidation activity associated with the induction of the GSTs including GSTA4.

Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the proliferation of cultured human tumor

7-Demethylsuberosin (7-demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory effects on PGE2 production with the IC50 values of 9.42 μM.

(+)-Columbianetin acetate (COLUMBIANETIN ACETATE) may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of (+)-Columbianetin acetate is a passive diffusion process without pH-dependent.

1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocker of the hKv1.5 channel and it prolongs the APD; therefore, it is an excellent candidate as an antiarrhythmic drug for atrial fibrillation.

2-Methyldecane is a colorless liquid used primarily as a solvent in organic synthesis reactions, and is also present in spice tobacco and cigarette smoke; it has low inhalation toxicity, and no deaths were observed in rats exposed to saturated vapor concentrations for 4 hours.

8-Hydroxybergapten may have anti-wrinkle activity.

Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as mosquito larvicidal agent.

Angelic Acid ((Z)-2-Methylbut-2-enoic acid) is a monocarboxylic unsaturated organic acid. Angelic acid esters are the active components of herbal medicine used against a wide range of various health disturbances including pains, fever, gout, heartburn, etc.

2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots, possesses acaricidal properties and can be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl)oxy]acetophenone.

(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) has antitumor and hypoglycemic effects, and can effectively inhibit the tumor growth of glioma and inhibit R-glucosidase activity.

α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.

2',4'-Dihydroxyacetophenone (Resacetophenone) is an alkyl-phenylketone.

Tokinolide B, isolated from Ligusticum porter rhizomes, mediates anti-inflammatory effects via Nur77 binding.

(±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone), a flavonoid extracted from Angelica keiskei, inhibits the calcium-activated chloride channel TMEM16A.(±)-Liquiritigenin induces an increase in apoptosis and an enhancement of caspase3 activity. (±)-Liquiritigenin induces increased apoptosis and enhanced caspase3 activity. (±)-Liquiritigenin is used in breast cancer research.

Picrasidine Q is an anticancer natural alkaloid that targets FGFR2, inducing apoptosis and G1 arrest in oesophageal squamous cell carcinoma (ESCC) cells.