Perfluorohexane (AF-0150), a perfluorocarbon (PFC)-based microbubble formulation, is an ultrasound contrast agent with developmental toxicity that induces memory deficits and neuroprotein downregulation through the NMDA receptor-mediated PKC-ERK/AMPK signaling pathway.Perfluorohexane interferes with estrous cycle, ovulation rate in mice, Perfluorohexane interferes with estrous cycle, ovulation rate, oocyte communication and calcium homeostasis in mice.
Perflubron (Perfluorooctyl bromide) can be emulsified with egg phospholipids (EYP) and displays exceptionally fast excretion characteristics. Perflubron(1-Bromoheptadecafluorooctane; Heptadecafluorooctyl bromide; Perfluorooctyl bromide) is a contrast medium for magnetic resonance imaging and sonography.
Gadoquatrane is a highly stable gadolinium-based MRI contrast agent that enhances soft tissue imaging by altering local magnetic fields to improve contrast. It possesses low permeability and high biocompatibility.
Iomeprol, a nonionic X-ray contrast agent, is characterized by its low osmotic pressure, stable chemical properties, and resistance to high temperature sterilization. It is extensively utilized in angiographic examinations of the vascular system, body cavities, and gastrointestinal tract [1].
Tc-BQ0413 specifically binds to prostate-specific membrane antigen (PSMA) with high affinity. When labeled with technetium-99m (Tc-99m), Tc-BQ0413 serves as an imaging agent for single-photon emission computed tomography (SPECT).