Thyroid hormone receptor(THR)

The thyroid hormone receptor (TR) is a type of nuclear receptor that is activated by binding thyroid hormone.TRs act as transcription factors, ultimately affecting the regulation of gene transcription and translation. These receptors also have non-genomic effects that lead to second messenger activation, and corresponding cellular response.

Cat. No.	Product name	CAS No.	Purity
T11101	DS08210767	2376334-75-5	98%
T11101	DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.
T29011	Triiodothyronine Sulfate	31135-55-4	98%
T29011	Triiodothyronine Sulfate is a prodrug to the Conventional Hormone Therapy of Hypothyroidism. Triiodothyronine sulfate is the main metabolite of thyroid hormone t...
T25455L	Glutaurine aceate	T25455L	98%
T25455L	Glutaurine aceate containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine aceate, as a hormone, is isolated from par...
T15699	L-Thyroxine sodium salt pentahydrate	6106-07-6	98%
T15699	L-Thyroxine sodium salt pentahydrate is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodot...
T15644	KAT681	373641-87-3	98%
T15644	KAT681 is a liver selective thyromimetic.
T7590	Taltirelin	103300-74-9	98%
T7590	Taltirelin is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ conc...
T1309	Propylthiouracil	51-52-5	98%
T1309	Propylthiouracil is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor.
T13072	Taltirelin acetate	1549593-23-8	98%
T13072	Taltirelin acetate is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic ...
T13492	3,5-Diiodothyropropionic acid	1158-10-7	98%
T13492	3,5-Diiodothyropropionic acid is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.0...
T1653	Liothyronine	6893-02-3	98%
T1653	Liothyronine is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.
T0952	Carbimazole	22232-54-8	98%
T0952	Carbimazole is an Imidazolium thyroid antagonist, which is rapidly transformed into MMI in vivo and can be converted into methidazole in vitro, and can be used i...
T1604	Tiratricol	51-24-1	98%
T1604	Tiratricol is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials s...
T3595	Resmetirom	920509-32-6	98%
T3595	MGL-3196 is a highly selective thyroid hormone receptor β (THR-β) agonist.
T5313	Sobetirome	211110-63-3	98%
T5313	Sobetirome is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
T0864	L-Thyroxine	51-48-9	98%
T0864	Levothyroxine is the major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling o...
T23673	AH-3960	862907-48-0	98%
T23673	AH-3960 is an thyroid hormone receptor-1 (PTHR1) agonist.
T5360	Eprotirome	355129-15-6	98%
T5360	Eprotirome, a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.
T1669	Liothyronine sodium	55-06-1	98%
T1669	Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyron...
T7578	REVERSE T3	5817-39-0	98%
T7578	reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
T9691L	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate		98%
T9691L	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membr...