Serine/threonin kinase

Serine threonine kinase belongs to protein kinase, which can phosphorylate the OH group of serine or threonine residues. Serine threonine kinases contain Rho kinase, Aurora kinase, AMP kinase, RAF kinase, Polo like kinase, PIM kinase, ATM kinase and other kinases. The cAMP/cGMP, Ca2+/calmodulin and diacylglycerol and multiple chenmical signals can regulate the activity of serine threonine kinases.

Cat. No.	Product name	CAS No.	Purity
T16931	SRPKIN-1	2089226-94-6	98%
T16931	SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).
T8957	CRT0066101	956121-30-5	98%
T8957	CRT0066101 is an inhibitor of PKD.
T8362	Benzamidine hydrochloride	1670-14-0	99.97%
T8362	Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, r...
T8535	GAK inhibitor 49	319492-82-5	99.93%
T8535	GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).
T8957L	CRT0066101 dihydrochloride(956121-30-5 free base)	2308510-39-4	99.92%
T8957L	CRT0066101 dihydrochloride is an inhibitor of PKD.
T1808	Kb-NB77-78	1350622-33-1	99.89%
T1808	kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).
TQ0104	CRT0066101 dihydrochloride	1883545-60-5	99.85%
TQ0104	CRT0066101 dihydrochloride is an effective and selective PKD inhibitor (IC50s: 1, 2.5 and 2 nM for PKD1, 2, and 3).
T1606	Fasudil	103745-39-7	99.84%
T1606	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T2458	CID755673	521937-07-5	99.84%
T2458	CID755673 is an effective and specific cell-active inhibitor for PKD (IC50: 182 nM); exhibits selective PKD1 inhibition when compared with PLK1, AKT, CAMKIIα, CA...
T9276	SBC-115337	423148-46-3	99.81%
T9276	SBC-115337 is a PCSK9 inhibitor.
T4524	SBC-110736	1629166-02-4	99.76%
T4524	SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor
T6283	Wortmannin	19545-26-7	99.76%
T6283	Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that bl...
T4291	(+)-Isocorydine hydrochloride	13552-72-2	99.72%
T4291	(+)-Isocorydine hydrochloride (Isocorydine HCl) is a eukaryote protein kinases Inhibitor.
T4058	R-IMPP	2133832-83-2	99.7%
T4058	R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted ...
T2391	Camostat mesylate	59721-29-8	99.69%
T2391	Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.
T3050	ML-7 hydrochloride	110448-33-4	99.61%
T3050	ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also...
TP1890L1	MLCK inhibitor peptide 18 acetate	TP1890L1	99.57%
TP1890L1	MLCK inhibitor peptide 18 acetate is a selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kinas...
T3060	Fasudil hydrochloride	105628-07-7	99.54%
T3060	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T7444	6-(Dimethylamino)purine	938-55-6	99.49%
T7444	6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor
T0610	Piceatannol	10083-24-6	99.39%
T0610	Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits...