Serine/threonin kinase

Serine threonine kinase belongs to protein kinase, which can phosphorylate the OH group of serine or threonine residues. Serine threonine kinases contain Rho kinase, Aurora kinase, AMP kinase, RAF kinase, Polo like kinase, PIM kinase, ATM kinase and other kinases. The cAMP/cGMP, Ca2+/calmodulin and diacylglycerol and multiple chenmical signals can regulate the activity of serine threonine kinases.

Cat. No.	Product name	CAS No.	Purity
T8957	CRT0066101	956121-30-5	98%
T8957	CRT0066101 is an inhibitor of PKD.
T16931	SRPKIN-1	2089226-94-6	98%
T16931	SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).
T24152	HTH-01-091	2000209-42-5	98%
T24152	HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK...
T1606	Fasudil	103745-39-7	98%
T1606	Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T5456	WNK-IN-11	2123489-30-3	98%
T5456	WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)
T4058	R-IMPP	2133832-83-2	98%
T4058	R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted ...
T11666	IPR-803	892243-35-5	98%
T11666	IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM....
T10547	BioE-1115	1268863-35-9	98%
T10547	BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).
T7017	WNK463	2012607-27-9	98%
T7017	WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).
T19763	Cetraxate hydrochloride	27724-96-5	98%
T19763	Cetraxate HCl is an oral gastrointestinal medication. It has a cytoprotective effect.
T9256	N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine	1071135-06-2	98%
T9256	N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine is a novel 2,6-naphthyridine identified by high throughput screen (HTS) as a dual protein...
T77501	TAO Kinase inhibitor 2	850467-77-5	98%
T77501	TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.
T13257	Upamostat	590368-25-5	98%
T13257	Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.
T72025	PCSK9-IN-10	368434-98-4	98%
T72025	PCSK9-IN-10 is a potent and orally active PCSK9 inhibitor with an IC 50 value of 6.4 µM. PCSK9-IN-10 increases the expression of LDLR protein and decreases the e...
T27525	HA-1004	91742-10-8	98%
T27525	HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.
T8676	FOY 251	71079-09-9	98%
T8676	FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
T10572L	BMT-124110 Formate	T10572L	98%
T10572L	BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase ...
T2153	1-NM-PP1	221244-14-0	98%
T2153	1 nM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
T1858	CID-797718	370586-05-3	98%
T1858	CID797718 is a protein kinase D1 (PKD1) inhibitor.
T5194	SPHINX31	1818389-84-2	98%
T5194	SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).