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Factor Xa

Factor X, also known by the eponym Stuart–Prower factor, is an enzyme  of the coagulation cascade. It is a serine endopeptidase (protease group S1, PA clan). Factor X is synthesized in the liver and requires vitamin K for its synthesis.Factor X is activated, by hydrolysis, into factor Xa by both factor IX (with its cofactor, factor VIII in a complex known as intrinsic Tenase) and factor VII with its cofactor, tissue factor (a complex known as extrinsic Tenase ). It is therefore the first member of the final common pathway or thrombin pathway.
Cat. No. Product name CAS No. Purity Chemical Structure
T68092 Letaxaban 870262-90-1 98%
Letaxaban is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.
T29215 Zifaxaban 1378266-98-8 98%
Zifaxaban is an orally active, competitive and selective inhibitor of factor Xa (FXa) with an IC50 of 11.1 nM for human FXa.Zifaxaban has a very high affinity, m...
T12736 Rivaroxaban-d4 1132681-38-9 98%
Rivaroxaban D4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent,selective and direct inhibitor of Factor Xa (FXa)(IC50:0.7 nM; Ki:0.4 nM).
T12782 RWJ-445167 226566-43-4 98%
RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.
T19488 O-Desmethyl apixaban sulfate sodium T19488 98%
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.
T0775 Coumarin 91-64-5 98%
Coumarin is a chemical compound/poison found in many plants, notably in high concentration in the tonka bean, woodruff, and bison grass. It has clinical value as...
T0372 Gabexate mesylate 56974-61-9 98%
Gabexate mesylate is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a ...
T67853 Rivaroxaban Impurity 1151893-81-0 98%
Rivaroxaban Impurity is a potent Blood-coagulation factor Xa inhibitor, IC50= 66 nM.
T27318 Fidexaban 183305-24-0 98%
Fidexaban is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays
T4341 Betrixaban 330942-05-7 98%
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...
T31206 Darexaban 365462-23-3 98%
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothr...
T4980 Betrixaban maleate 936539-80-9 98%
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...
T20454 4-Chlorophenylurea 140-38-5 98%
4-Chlorophenylurea is a novel orally bioavailable inhibitor of factor Xa.
T10174 5-R-Rivaroxaban 865479-71-6 98%
5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor (IC50 0.7 nM; Ki 0...
T6531 Heparin sodium salt 9041-08-1 98%
Heparin sodium is a sulfated polysaccharide, which belongs to the family of glycosaminoglycans. It is utilized as an anticoagulant and interacted with diverse p...
T4076 Fondaparinux sodium 114870-03-0 98%
Fondaparinux Sodium is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
T2368 Edoxaban Tosylate Monohydrate 1229194-11-9 98%
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
T66256 Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 503614-91-3 98%
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagula...
T39463 Asundexian 2064121-65-7 98%
Asundexian is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiti...
T1736 Apixaban 503612-47-3 98%
Apixaban is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the c...
Letaxaban
T68092
Letaxaban is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.
Zifaxaban
T29215
Zifaxaban is an orally active, competitive and selective inhibitor of factor Xa (FXa) with an IC50 of 11.1 nM for human FXa.Zifaxaban has a very high affinity, m...
Rivaroxaban-d4
T12736
Rivaroxaban D4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent,selective and direct inhibitor of Factor Xa (FXa)(IC50:0.7 nM; Ki:0.4 nM).
RWJ-445167
T12782
RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.
O-Desmethyl apixaban sulfate sodium
T19488
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.
Coumarin
T0775
Coumarin is a chemical compound/poison found in many plants, notably in high concentration in the tonka bean, woodruff, and bison grass. It has clinical value as...
Gabexate mesylate
T0372
Gabexate mesylate is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a ...
Rivaroxaban Impurity
T67853
Rivaroxaban Impurity is a potent Blood-coagulation factor Xa inhibitor, IC50= 66 nM.
Fidexaban
T27318
Fidexaban is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays
Betrixaban
T4341
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...
Darexaban
T31206
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothr...
Betrixaban maleate
T4980
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among ...
4-Chlorophenylurea
T20454
4-Chlorophenylurea is a novel orally bioavailable inhibitor of factor Xa.
5-R-Rivaroxaban
T10174
5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor (IC50 0.7 nM; Ki 0...
Heparin sodium salt
T6531
Heparin sodium is a sulfated polysaccharide, which belongs to the family of glycosaminoglycans. It is utilized as an anticoagulant and interacted with diverse p...
Fondaparinux sodium
T4076
Fondaparinux Sodium is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
Edoxaban Tosylate Monohydrate
T2368
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
T66256
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate has an inhibitory effect on coagula...
Asundexian
T39463
Asundexian is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiti...
Apixaban
T1736
Apixaban is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the c...
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