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By Target- Caspase
- RIP kinase(1)
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Results for "
z vad fmk
" in TargetMol Product Catalog- Inhibitors & Agonists4
Z-VAD-FMK
Cited
Z-VAD(OH)-FMK, Caspase Inhibitor VI
T7020161401-82-7
Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not inhibit UCHL1 activity, even at concentrations up to 440 μM.
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CitedZ-VAD(OMe)-FMK Cited
Z-Val-Ala-Asp(OMe)-FMK, Z-VAD-FMK
T6013187389-52-2
Z-VAD(OMe)-FMK is a pan-caspase inhibitor with irreversible properties; Z-VAD(OMe)-FMK is also an inhibitor of ubiquitin C terminal hydrolase L1 (UCHL1), which is irreversibly modified by targeting the UCHL1 active site.
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Cited(Iso)-Z-VAD(OMe)-FMK
T88862634911-81-2
(Iso)-Z-VAD(OMe)-FMK is an isomer of Z-VAD(OMe)-FMK, which is a pan-caspase inhibitor with irreversible properties. Z-VAD(OMe)-FMK is also an inhibitor of ubiquitin C-terminal hydrolase L1 (UCHL1), irreversibly modified by targeting the UCHL1 active site.
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RI-962
RI962
T734932763831-53-2
RI-962 is a potent and selective inhibitor of RIPK1 that dose-dependently protects cells from necrotic apoptosis induced by TNFα, Smac mimics, and Z-VAD-FMK by inhibiting RIPK1, RIPK3, and MLKL phosphorylation with EC50=10.0 nM~17.8 nM, and improves survival in mice in two models of inflammation.
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