vigabatrin

Vigabatrin (Sabril), an analogue of gamma-aminobutyric acid, is an irreversible inhibitor of 4-aminobutyrate Transaminase responsible for the catabolism of γ-aminobutyric acid.

Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), which irreversibly inhibits the catabolism of GABA by GABA transaminase.

Vigabatrin-CoA (Vigabatrin-coenzyme A) is a derivative of coenzyme A.

Rac-Vigabatrin-13C,D5 hydrochloride Salt (Standard) is a reference standard of Rac-Vigabatrin-[13C,D5] Hydrochloride Salt intended for quantitative analysis, quality control, and related biochemical research applications.

OV329 hydrochloride is a highly potent, mechanism-based irreversible inhibitor of gamma-aminobutyric acid transaminase (GABA-AT). By inhibiting GABA degradation, it increases GABA levels in the brain, thereby enhancing central inhibitory neurotransmission. OV329 hydrochloride is being developed for research into refractory epilepsy and seizure-related conditions. Preliminary studies indicate that it exhibits stronger anticonvulsant activity than vigabatrin and may offer superior ocular safety.

CPP-115 is a GABA-aminotransferase inhibitor and a high-affinity vigabatrin analogue.