venlafaxine

Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.

Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a cyclohexanol and phenylethylamine derivative functioning as a serotonin and noradrenaline reuptake inhibitor (SNRI) used as an antidepressive agent.

(S)-O-Desmethyl Venlafaxine N-Oxide, an N-oxide derivative of (S)-O-Desmethyl Venlafaxine, is an active metabolite of the serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant Venlafaxine[1][2].

(S)-Venlafaxine, the (S)-configuration of Venlafaxine, is an orally active, potent serotonin (5-HT) norepinephrine (NE) reuptake dual inhibitor with antidepressant activity [1].

(S)-Dehydro Venlafaxine is an inactive S-enantiomer of Dehydro Venlafaxine. Dehydro Venlafaxine is an impurity of Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a potent serotonin (5-HT) norepinephrine (NE) reuptake dual inhibitor [1] [2] .

(±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a minimum effective dose (MED) of 10 mg/kg.

(+ -)-Venlafaxine-d6 HCl is a deuterated compound of (+ -)-Venlafaxine HCl. (+ -)-Venlafaxine HCl has a CAS number of 99300-78-4. Venlafaxine hydrochloride is a cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT.

(R)-Desmethyl Venlafaxine-d6 is a deuterated compound of (R)-Desmethyl Venlafaxine.

Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive agent.

Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).

N,N,O-Tridesmethylvenlafaxine (Tridesmethylvenlafaxine) is a huamn endogenous metabolite.

SD-254 is a deuterium analog of Effexor, with fewer side effects and a longer half-life.

Melperone hydrochloride is a butyrophenone neuroleptic and an inhibitor of the CYP2D6 catalyzed O-demethylation of venlafaxine.