urocortin acetate

Urocortin (rat) acetate is a potent, selective CRFR agonist with Ki values of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α, and mouse CRF2β, respectively. Urocortin (rat) acetate exhibits cardioprotective, anti-inflammatory, and immunomodulatory activities. Urocortin (rat) acetate can be used in cardiovascular protection and immune-inflammatory research.

Urocortin II, human acetate, is a selective endogenous peptide agonist of type 2 corticotropin-releasing factor (CRF2) receptors, used to study the role of CRF2 receptors in feeding behavior.

Urocortin, human acetate is an endogenous peptide belonging to the corticotropin-releasing factor (CRF) family. By binding to and activating the CRF2 receptor with high affinity (and the CRF1 receptor moderately), it exerts critical neuroendocrine regulatory effects in modulating cardiovascular homeostasis, suppressing appetite, and mitigating stress-induced anxiety behaviors in pharmacology models.