triglycerides — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14933	Cetaben		Others
	Cetaben is a PPARα-independent peroxisome proliferator and is a non-fibrate hypolipidemic drug. It potent reduces the concentration of cholesterol and triglycerides.		Others
T14862	Caprylic/Capric Triglyceride		Others
	Caprylic/Capric Triglyceride, a compound consisting of triglycerides and esters derived from fractionated vegetable oil, and fatty acids from coconut and palm kernel oils, serves as a food additive and is utilized in cos...		Others
T9766	GW590735		PPAR
	GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used in dyslipidemia studies.		PPAR
T2499	Torcetrapib	CP-529414	CETP
	Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to exces...		CETP
T1676	Rosuvastatin	ZD 4522	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting...		Potassium Channel , HMG-CoA Reductase , Autophagy
T1510	Rosuvastatin calcium	ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.		Potassium Channel , HMG-CoA Reductase , Autophagy
T19864	Xenalipin	BW 207U	Others
	Xenalipin (BW 207U) has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.		Others
T27691	JNJ-DGAT2-A	JNJDGAT2A	Transferase
	JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about the synthesis of triglycerides.		Transferase
T9106	E1231		Sirtuin
	E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression.		Sirtuin
T19861	Niceritrol	Perycit,Cardiolipol,Bufor	Others
	Niceritrol (Cardiolipol) is a niacin ester that reduces cholesterol and triglycerides in total plasma and in the VLD and LD lipoprotein fractions.		Others
T16018	MB-07811	VK-2809	Thyroid hormone receptor(THR)
	MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity. MB-07811 is an agonist of liver-targeted THR-β.		Thyroid hormone receptor(THR)
T0841	Bezafibrate	BM15075	PPAR
	Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES. It decreases LOW-DENSITY LIPOPROTEINS and increases HIGH-DENSITY LIPOPROTEINS.		PPAR
TN2364	Sudan IV	Solvent Red 24,C.I. 26105	Others
	Sudan IV (Solvent Red 24) is a lysochrome (fat-soluble dye) diazo dye used for the staining of triglycerides，lipids and lipoproteins on frozen paraffin sections.		Others
T8276	Methyl palmitoleate		Others
	Palmitoleic acid methyl ester is an ester version of palmitoleic acid, an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue.		Others
T21383	D-Thyroxine	Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine	Others
	D-Thyroxine (Dextroxin) could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles.		Others
T2P2919	(2S,3R,4S)-4-Hydroxyisoleucine	(4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine	PI3K
	(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secr...		PI3K
T19057	Solvent Blue 35	Sudan Blue II,Oil Blue 35	Others
	Solvent Blue 35 (Sudan Blue II) (Sudan Blue II) is a dye used for coloring hydrocarbon-based and alcoholic solvents. It is used for staining triglycerides in animal tissues.		Others
T3771	Methyl protodioscin	Smilax saponin B,NSC-698790	Apoptosis
	Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in h...		Apoptosis
T15821	LY518674	LY-674	PPAR
	LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis. LY518674 is an effective and selective PPARα agonist (EC50: 42 nM for human PPARα).		PPAR
T5227	Tricaprin	Tridecanoin,Glyceryl tridecanoate,Glycerol Tridecanoate,TG(10:0/10:0/10:0),Glycerol tricaprate	Others , Endogenous Metabolite
	Tricaprin (Glycerol Tridecanoate) is also known as triacylglycerols or triacylglycerides. The triglycerides are rebuilt in the blood from their fragments and become constituents of lipoproteins, which deliver the fatty a...		Others , Endogenous Metabolite