tracer

Naphthoresorcinol (1,3-Dihydroxynaphthalene) is a fluorescent dye with an excitation wavelength (λex) of 330 nm and an emission wavelength (λem) of 380 nm.

JAK2 JH2 Tracer is a fluorescent probe for the JAK2 JH2 domain (Kd: 0.2 μM).

Lucifer Yellow CH dipotassium is a water-soluble fluorescent tracer that labels endocytosis vesicles in cells.Lucifer Yellow CH dipotassium excites and emits at a maximum wavelength of 430 nm and 540 nm, respectively.

Fluorescein (Solvent Yellow 94) is a phthalic indicator dye, use as a synthetic fluorescent tracer.

Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) is an inhibitor of Rous-associated virus 2 reverse transcriptase. Alizarin Complexone can be used as a calcium-tracer and a chelating agent for biological studies.

Fluorescein Sodium (VST-1001) is a phthalic indicator dye. It is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma.

DiI (DiIC18(3)) is a lipophilic membrane dye commonly used as a long-term tracer for neurons and other cells. DiI fluoresces very weakly before it enters the cell membrane, and only after it enters the cell membrane can it be excited to emit a strong orange-red fluorescence (λex=549 nm, λem=565 nm).

FITC-Dextran (MW 60,000-76,000) is a fluorescein isothiocyanate (FITC)-labeled dextran fluorescent probe that is commonly used as a tracer molecule to label and track the action of cells or other biomaterials on semipermeable membranes.

BODIPY-FL staurosporine (Compound 8a) is a fluorescent probe based on staurosporine, exhibiting high specificity for tyrosine kinases (TK) and tyrosine kinase-like (TKL) families. This compound holds the potential to develop binding assays for kinases that are not recommended for use with kinase Tracer 236, such as PIM3, CDC42BPG, MAP2K7, TXK, and SIK3.

Difluorocarboxyfluorescein cadaverine, 5-isomer, is a carbonyl-reactive moiety used for modifying carboxyl groups via a stable amide bond in the presence of activators such as EDC or DCC, or activated esters like NHS esters. Additionally, it serves as a polar tracer and an active dye for labeling proteins through its carboxylic acid component.

FITC-Dextran (MW 1000) is a compound classified under fluorescent dyes. It is commonly utilized in biomedical research as a tracer molecule to label and track cells or other biological materials. Composed of fluorescein isothiocyanate (FITC) and dextran, the latter being a complex carbohydrate derived from starch, this combination forms a stable fluorescent tracer suitable for microscopic observation or quantification using specialized detection equipment.

18:1 PE TopFluor AF 594 (triammonium) is a fluorescently labeled phospholipid probe. It can be utilized as a fluorescent tracer in lipid nanoparticles (LNPs) and shows potential for use in drug delivery systems.

Rhodamine B isothiocyanate (RITC) is a cell-permeant fluorogenic dye most often used as a conjugate to antibodies and proteins for fluorescence detection in microscopy. It displays excitation/emission maxima of 570/595 nm, respectively, and can be used in conjunction with immunohistochemistry for multi-labeling studies. It has also been used as an anterograde and retrograde tracer in neurons and in nanoparticles to detect apoptosis.

True blue is a fluorescent neuronal retrograde tracer that labels the nucleus, nucleolus, cell body, proximal dendrites, and axons of neurons. It displays excitation emission maxima of 373 404 nm, respectively.

DiO (DiOC18(3)) is a fluorescent lipophilic tracer and can be widely used to label cells, organelles, liposomes, viruses, and lipoproteins.

5-diacetate FAM NHS (5-CFDA SE) is a cell-permeable fluorescent tracer for use in fluorescence microscopy and flow cytometry, Ex=492 nm, Em=517 nm.

Patent Blue V (Acid blue 1), a biological dye, serves as an intraocular stain in retinectomy—surgical removal of the inner limiting membrane (ILM). Its use facilitates the complete excision of premembrane structures in vitreoretinal surgeries. Spectral analysis reveals that Patent Blue V absorbs strongly below 450 nm and above 600 nm, exhibiting a blue-green hue. Additionally, it functions as a tracer in lymphangiography to guide the surgical removal of cancerous lymph nodes [1][2].

Pyrromethene 650 (PM650) is a green-fluorescent polar tracer dye utilized for studying membrane fusion, lysis, and gap-junctional communication, as well as for detecting volume changes in cells or liposomes.

Pyrromethene 556 (PM556) is a green-fluorescent polar tracer dye used in studying membrane fusion, lysis, gap-junctional communication, and in monitoring cell and liposome volume changes.

Lucifer Yellow Iodoacetamide Dipotassium is a thiol-reactive (sulfhydryl-reactive) fluorescent tracer utilized for labeling proteins.

3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is a pteridine-based fluorescent guanosine analogue and DNA uptake tracer, extensively utilized for investigating DNA binding and dynamics, with an absorbance peak at 350 nm and an emission peak at 430 nm [1].

4-Di-10-ASP, a fluorescent lipophilic tracer (Excitation 485 nm; Emission 620 nm), specifically stains phospholipid membranes [1] [2].

CellTracker Green BODIPY (compound 31), a green fluorescent dye, serves as an intracellular environmental tracer [1].

FSY-OSO2F, after labeling with isotope 18 F, is used as an amino acid tracer for subcutaneous MCF-7 tumors. It shows uptake in MCF-7 cells through regulation of L-Tyr, ASC, and ASC2 transporters, and also visualizes the U78MG glioma labeled with 18 F [1].