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Cholera toxin B subunit, from vibrio cholerae

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Catalog No. TRP-00235Cas No. 131096-89-4

Cholera toxin B subunit, from Vibrio cholerae (CTB, from vibrio cholerae), is non-toxic to cells and lacks inherent adenylate cyclase activity. It adheres to cells by binding to ganglioside GM1.8. Research indicates that this subunit is an excellent marker for microglia due to their surface richness in ganglioside GM1, though it is not as effective for oligodendrocytes or astrocytes. Additionally, CTB is reported to be an excellent tracer for studying axonal transport using immunohistochemistry and has been widely used as a marker for membrane lipid rafts.

Cholera toxin B subunit, from vibrio cholerae

Cholera toxin B subunit, from vibrio cholerae

😃Good
Catalog No. TRP-00235Cas No. 131096-89-4
Cholera toxin B subunit, from Vibrio cholerae (CTB, from vibrio cholerae), is non-toxic to cells and lacks inherent adenylate cyclase activity. It adheres to cells by binding to ganglioside GM1.8. Research indicates that this subunit is an excellent marker for microglia due to their surface richness in ganglioside GM1, though it is not as effective for oligodendrocytes or astrocytes. Additionally, CTB is reported to be an excellent tracer for studying axonal transport using immunohistochemistry and has been widely used as a marker for membrane lipid rafts.
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Bioactivity
Description
Cholera toxin B subunit, from Vibrio cholerae (CTB, from vibrio cholerae), is non-toxic to cells and lacks inherent adenylate cyclase activity. It adheres to cells by binding to ganglioside GM1.8. Research indicates that this subunit is an excellent marker for microglia due to their surface richness in ganglioside GM1, though it is not as effective for oligodendrocytes or astrocytes. Additionally, CTB is reported to be an excellent tracer for studying axonal transport using immunohistochemistry and has been widely used as a marker for membrane lipid rafts.
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Cas No.131096-89-4
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Storagekeep away from direct sunlight | store at 4°C

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