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tpl-2 kinase inhibitor 1

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Tpl2 Kinase Inhibitor 1
T17145871307-18-5
Tpl2 Kinase Inhibitor 1 is a potent, reversible, and highly selective ATP-competitive inhibitor of Tpl2 (MAP3K8/COT) serine/threonine kinase, with an IC₅₀ of 50 nM for Tpl2 kinase inhibition. In vitro, Tpl2 Kinase Inhibitor 1 inhibits LPS-induced TNF-α release from human primary monocytes (IC₅₀ = 0.7 μM). Tpl2 Kinase Inhibitor 1 can be used in research on inflammatory responses and certain cancers.
  • $64
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Tpl2 Kinase Inhibitor 1 hydrochloride
T2119462934185-09-6
Tpl2 Kinase Inhibitor 1 hydrochloride is a selective Tpl2 inhibitor with an IC50 value of 50 nM. Tpl2 encompasses COT kinase and MAP3K8, and this inhibitor is applicable for research related to inflammatory responses and certain types of cancer.
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10-14 weeks
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