tco-peg-4-tco

TCO-PEG4-TCO is a PEG-based linker used in PROTACs that connects two ligands critical for PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

BDP FL-PEG4-TCO is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

TCO-PEG4-acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands crucial for forming PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

(S)-TCO-PEG4-acid is a PEG-based linker for PROTACs, joining two essential ligands critical for PROTAC molecule formation, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG4-biotin is a PROTAC linker belonging to the PEG class.TCO-PEG4-biotin can be used to synthesise a range of PROTAC molecules.

TCO-PEG4-NHS ester is a PROTAC linker bridge in the PEG class, used for synthesizing various PROTAC molecules. As a cleavable and synthetic ADC, it is also utilized in the synthesis of antibody-drug conjugates (ADCs).

DBCO-PEG4-SS-TCO is a cleavable 4-unit polyethylene glycol (PEG) linker crucial for the synthesis of antibody-drug conjugates (ADCs)[1], facilitating the connection of the drug payload to the antibody and enabling targeted drug delivery.

TCO-PEG4-amine is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the selective protein degradation by leveraging the ubiquitin-proteasome system within cells. [PROTACs]

TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

(E)-TCO-PEG4-NHS ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Tetrazine-PEG4-amine (hydrochloride) serves as a cleavable 4-unit PEG ADC linker and a click chemistry reagent in the synthesis of antibody-drug conjugates (ADCs) [1]. It features a Tetrazine group capable of undergoing an inverse electron demand Diels-Alder reaction (iEDDA) with molecules that contain TCO groups.

Methyltetrazine-PEG4-hydrazone-DBCO, a cleavable 4-unit PEG ADC linker, serves as a click chemistry reagent in the synthesis of antibody-drug conjugates (ADCs) [1]. This compound features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-bearing molecules. It also includes a Tetrazine group capable of engaging in an inverse electron demand Diels-Alder reaction (iEDDA) with TCO-bearing molecules.

Methyltetrazine-PEG4-aldehyde serves as a cleavable 4-unit PEG ADC linker in antibody-drug conjugates (ADCs) synthesis [1]. It functions as a click chemistry reagent, featuring a Tetrazine group capable of undergoing an inverse electron demand Diels-Alder reaction (iEDDA) with TCO-containing molecules.

Tetrazine-diazo-PEG4-biotin functions as a cleavable 4-unit PEG ADC linker in the preparation of antibody-drug conjugates (ADCs) [1]. This compound acts as a click chemistry reagent, incorporating a Tetrazine group capable of conducting an inverse electron demand Diels-Alder reaction (iEDDA) with molecules possessing TCO groups.

(S)-TCO-PEG4-NHS ester, an ADC linker with four PEG units, utilizes its TCO group to facilitate an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine-containing molecules.

Me-Tet-PEG4-NHS, an ADC Linker featuring four PEG units, leverages its Tetrazine group for a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds containing TCO groups.

Me-Tet-PEG4-NH2, an ADC Linker featuring 4 PEG units, utilizes its Tetrazine group to participate in an inverse electron demand Diels-Alder reaction (iEDDA) with compounds containing TCO groups.

Me-Tet-PEG4-Maleimide, an ADC Linker, incorporates four PEG units and features a Tetrazine group capable of engaging in a specific inverse electron demand Diels-Alder reaction (iEDDA) with TCO group-containing compounds. Additionally, its maleimide group (-Maleimide) is susceptible to degradation in aqueous environments, a characteristic that has been explored in drug delivery research.

Me-Tet-PEG4-NHBoc, an ADC Linker comprising 4 PEG units, employs its Tetrazine group to participate in a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds containing TCO groups. This capability allows for precise chemical bonding essential for targeted drug delivery applications.