tannin

Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM).

Cinnamtannin D2 (compound 13), a tannin derived from Vaccinium vitis-idaea L., boasts isolation from the aforementioned source [1].

Cinnamtannin B2 is a type of cinnamtannin component that can be isolated and extracted from Vaccinium vitis-idaea L.

Aceritannin is a useful organic compound for research related to life sciences. The catalog number is T124250 and the CAS number is 76746-56-0.

Cinnamtannin B-1 (LDN 0022358) is an A-type proanthocyanidin contained in several plant species such as Vaccinium vitis-idaea, Laurus nobilis L., Cinnamomum zeylanicum, and Lindera umbellata. It is a potent antioxidant and protective agent against oxidative stress and apoptosis in human platelets. It is a Cox-2 inhibitor.

Cinnamtannin A2 is a natural product and procyanidin tetramer that enhances GLP-1 and insulin secretion in mice. It protects against renal injury by reducing KIM-1 and NGAL expression and exhibits antioxidant activity.

Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.

Gallotannin is a useful organic compound for research related to life sciences and the catalog number is T65451.

Chinese gallotannin, derived from Galla Chinensis, is a non-specific promiscuous inhibitor of various enzymes. It is a potent inhibitor of human salivary α-amylase, with a Ki value of 0.82 μg/mL. Mechanistic studies reveal that gallotannins exert their inhibitory effects through the formation of aggregates, which serve as the active species in the inhibition process. Beyond its role in carbohydrate metabolism, it exhibits inhibitory activity against telomerase, fatty acid synthase, and 5α-reductase, making it a versatile tool for research in diabetes, oncology, and metabolic disorders.

Hamamelitannin (Standard) is a reference standard for research and analysis in studies involving Hamamelitannin. Hamamelitannin a polyphenol extracted from the bark of Hamamelis virginiana, has cytotoxic and antibiofilm activities，and is a quorum-sensing (QS) inhibitor.It increases antibiotic susceptibility of staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release.It also has a high protective activity on cell damage induced by peroxides.

Cinnamtannin A2 (Standard) is a reference standard for research and analysis in studies involving Cinnamtannin A2. Cinnamtannin A2 is a natural product and procyanidin tetramer that enhances GLP-1 and insulin secretion in mice. It protects against renal injury by reducing KIM-1 and NGAL expression and exhibits antioxidant activity.

Cinnamtannin D1 is an orally active polyphenolic compound that modulates the Th17/Treg cell balance by inhibiting AHR expression. It reduces apoptosis and ROS in INS-1 cells and primary cultured mouse islets induced by Palmitic acid (PA). Cinnamtannin D1 mitigates Th17 cell differentiation by downregulating p-STAT3/RORγt and enhances Treg cell differentiation by upregulating p-STAT5/Foxp3. In a collagen-induced arthritis (CIA) mouse model, it demonstrates excellent anti-arthritic efficacy. Cinnamtannin D1 is applicable for rheumatoid arthritis (RA) research.

Cassiatannin A is a tetrameric procyanidin identified in cinnamon (Cinnamomum cassia). It exhibits COX-2 inhibitory activity, with inhibition rates of 38%, 52%, and 97% at concentrations of 10, 100, and 1000 μg/mL, respectively. Cassiatannin A is applicable in inflammation research.

Parameritannin A-1 is a tetrameric proanthocyanidin (PAC) that can be isolated from the bark of plants belonging to the Apocynaceae family. It acts as a COX-2 inhibitor and also suppresses the activity of phospholipase A2 (PLA2).

Lindetannin is an A-type proanthocyanidin trimer identified in the bark of Cinnamomum (cinnamon trees). Proanthocyanidins are a class of polyphenolic compounds found widely in higher plants, composed of electrophilic flavanyl units. They serve as antioxidants and anti-cancer agents and exhibit anti-inflammatory, cardioprotective, antibacterial, and antifungal properties, making them useful for researching conditions such as chronic venous insufficiency, capillary fragility, sunburn, and retinopathy.

Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a high protective activity on cell damag

Procyanidin A3 (Cinnamtannin A3; Cinnamtannin II) is a subclass of Proanthocyanidins, a group of polyphenolic compounds prevalent in higher plants composed of electrophilic flavan-3-ol units. Proanthocyanidins serve as antioxidants and anticancer agents, and they also exhibit anti-inflammatory, cardioprotective, antibacterial, and antifungal properties, useful for studying chronic venous insufficiency, capillary fragility, sunburn, and retinopathy.

Oenothein B is a specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B shows antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties.

CCR-11 is a tannin-containing derivative with antimicrobial activity. CCR-11 inhibits the proliferation of B. subtilis and HeLa cells. CCR-11 inhibits bacterial proliferation and bacterial cytoplasmic division by inhibiting FtsZ assembly and GTPase activity. CCR-11 has potential anti-tumor activity and can be used to study breast cancer and pediatric myelodysplasia.

SARS-CoV-2 Mpro-IN-22 (compound 4) is an effective inhibitor of the SARS-CoV-2 main protease (Mpro), with an IC50 of 1.2 µg/mL. This hydrolyzable tannin exhibits no significant cytotoxic activity in A549 and HUVEC cell lines.

2′,4′,6′-trihydroxyacetophenone 4′-O-[4,6-(S)-hexahydroxydiphenoyl]-β-glucoside is a structurally complex polyphenolic glycoside that belongs to the category of plant tannin-related secondary metabolites and is commonly used in life science experiments.

Procyanidin B3-3-O-gallate is a naturally occurring tannin compound found in the plant Sanguisorba officinal.

2,3,4,6-Tetragalloylglucose is a hydrolyzable tannin with antioxidant properties, exhibiting DPPH radical scavenging activity (IC50=11.35 μM). It can be isolated from the inner peel of Juglans regia (walnut).

BIFUHALOL is a polyphenolic tannin identified in S. latissima.