tachyarrhythmias

Atropine (DL-Hyoscyamine) Sulfate is the sulfate salt of atropine, a naturally-occurring alkaloid isolated from the plant Atropa belladonna. Atropine functions as a sympathetic, competitive antagonist of muscarinic cholinergic receptors, thereby abolishing the effects of parasympathetic stimulation.

Atropine sulfate (Sulfatropinol) is a competitive antagonist for muscarinic acetylcholine receptor.

Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM. It is a Class III antiarrhythmic compound and can be used in the study of tachyarrhythmias.

Pilsicainide HCl (SUN 1165) is a pure sodium channel blocker

Clofilium phosphate (LY 150378) is an antiarrhythmic/antifibrillatory agent. It significantly prolongs the action potential duration and the effective refractory period in canine Purkinje fibers and raises the ventricular fibrillation threshold, thereby reducing the risk of reentrant arrhythmias. Some cases of ventricular fibrillation may spontaneously revert to sinus rhythm. Clofilium phosphate is used in research related to ventricular fibrillation, arrhythmias, and ventricular tachyarrhythmias.

Adaprolol maleate is a beta-blocker and opthalmic which may be used in the treatment of Glaucoma or other ailments of the eye. Adaprolol has marked electrophysiologic effects. Its major action was on sinus node; it prolonged the basic sinus cycle length and had significant effect on intrinsic automaticity as reflected by the prolonged corrected sinus node recovery time and sinuatrial conduction time. There was, also, direct effect on atrial function and AV nodal function. Adaprolol prolonged the effective refractory period of the His-Purkinje system and the ventricle. The potency of adaprolol's electrophysiologic effects are higher compared to other widely used beta-blockers. Adaprolol appears to be a potent beta-blocker with particularly strong antiarrhythmic effect and it would be very useful in the treatment of both supraventricular and ventricular tachyarrhythmias and ectopic beats.

Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormally fast heart rhythms).

Flecainide-D4 Acetate is a deuterated compound of Flecainide Acetate. Flecainide Acetate (T7219) has a CAS number of 54143-56-5. Flecainide (acetate) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).